陈慧敏,彭 枫.食管鳞癌免疫治疗临床研究新进展[J].肿瘤学杂志,2018,24(11):1051-1055. |
食管鳞癌免疫治疗临床研究新进展 |
Progress on Immunotherapy for Esophageal Squamous Cell Carcinoma |
投稿时间:2018-01-29 |
DOI:10.11735/j.issn.1671-170X.2018.11.B003 |
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中文关键词: 食管鳞状细胞癌 免疫检查点抑制剂 细胞治疗 肿瘤疫苗 |
英文关键词:esophageal squamous cell carcinoma immunocheckpoint inhibitors adoptive cellular immunotherapy peptide vaccines |
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中文摘要: |
摘 要:目前,针对食管鳞状细胞癌免疫治疗的多项临床研究正在进行。全文综述了免疫检查点抑制剂、过继性细胞免疫治疗、肿瘤疫苗等多种免疫治疗方法在食管鳞状细胞癌中的临床研究进展。目前免疫检查点抑制剂在食管鳞状细胞癌中取得了初步成效,肽段疫苗、过继性细胞免疫治疗也显示出治疗食管鳞状细胞癌的潜力,这些为改善晚期食管鳞状细胞癌患者生存带来新的希望。 |
英文摘要: |
Abstract:At present,multiple clinical studies of immunotherapy for esophageal squamous cell carcinoma(ESCC) are ongoing. This article reviews the progress of immunotherapy in the ESCC,including immunocheckpoint inhibitors,adoptive cellular immunotherapy and tumor vaccines. Currently,immunocheckpoint inhibitors have achieved initial success in ESCC. Peptide vaccines and adoptive cellular immunotherapy also show potential for the treatment of ESCC,which will bring new hope to improve the survival of patients with advanced ESCC. |
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