| 刘 琳,沈 攀,刘福川.134例老年胃癌患者临床病理特征与术后并发症的危险因素分析[J].肿瘤学杂志,2018,24(8):795-799. |
| 134例老年胃癌患者临床病理特征与术后并发症的危险因素分析 |
| The Clinicopathological Features and Risk Factors of Postoperative Complications in 134 Elderly Patients with Gastric Cancer |
| 投稿时间：2017-06-13 |
| DOI：10.11735/j.issn.1671-170X.2018.08.B009 |
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| 中文关键词: 胃肿瘤 高龄 临床病理特征 并发症 危险因素 |
| 英文关键词:gastric cancer elderly clinicopathological features complication risk factors |
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| 中文摘要: |
| 摘 要：［目的］ 探讨老年胃癌患者的临床病理特征与术后并发症危险因素。［方法］ 回顾性分析行胃癌手术治疗且随访信息完整的134例老年胃癌患者的临床资料，根据Clavien-Dindo并发症分级标准分为并发症组和对照组，通过单因素分析和多因素分析临床病理特征与术后并发症发生的相关性。［结果］ 134例患者根据Clavien-Dindo分级标准其中出现Ⅱ级及以上并发症的患者共38例（并发症组），出现Ⅰ级及以下并发症的患者为96例（对照组）。单因素分析结果显示年龄、共患基础疾病种类数、病灶个数、手术方式、手术范围、淋巴结清扫范围、合并脏器切除、围手术期输血是老年胃癌患者术后出现并发症的危险因素（P<0.05）。多因素Logistic回归分析结果表明合并基础病种类数(OR=2.58，95%CI：1.39～4.67，P=0.006)、胸腹联合手术(OR=1.57，95%CI：1.22~5.62，P=0.015)、合并脏器切除(OR=1.86，95%CI：1.34～6.98，P=0.022)、围手术期输血(OR=1.33，95%CI：1.18～5.63，P=0.034)是老年胃癌患者术后并发症发生的独立危险因素。［结论］ 老年胃癌患者有其独特的病理生理学特征，合并基础病种类数、胸腹联合手术、合并脏器切除、围手术期输血是术后并发症发生的独立危险因素。 |
| 英文摘要: |
| Abstract：［Objective］ To investigate the clinicopathological features and postoperative complications in the elderly patients with gastric cancer. ［Methods］ Clinical data of 134 elderly patients with gastric cancer who underwent gastrectomy were enrolled. They were divided into complication group and control group according to Clavien-Dindo classification，and single factor analysis and multi factor analysis were applied to analysis the risk factors of postoperative complications in the elderly patients with gastric cancer. ［Results］ There were 38 cases in complication group and 96 cases in control group. Univariate analysis showed that years，both disease species number，number of lesions，surgical methods，surgical range，lymph node dissection，combined organ resection，perioperative blood transfusion were risk factors for complications in elderly patients with gastric cancer after operation(P<0.05). Multivariate Logistic regression analysis showed that disease species number(OR=2.58，95%CI：1.39～4.67，P=0.006)，thoracoabdominal combined surgery(OR=1.57，95%CI：1.22～5.62，P=0.015)，combined organ resection(OR=1.86，95%CI：1.34～6.98，P=0.022)，perioperative blood transfusion(OR=1.33，95%CI：1.18～5.63，P=0.034) were the independent risk factors for complications in elderly patients with gastric cancer after operation. ［Conclusion］Elderly patients with gastric cancer have their unique pathophysiological features，and disease species number，abdominal and abdominal combined surgery，combined organ resection，perioperative blood transfusion are the independent risk factors for complications after operation. |
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