| 胡雪飞,张碧波.支撑喉镜下低温射频等离子手术在早期声门型喉癌术中的应用[J].肿瘤学杂志,2018,24(4):351-354. |
| 支撑喉镜下低温射频等离子手术在早期声门型喉癌术中的应用 |
| Application of Support Laryngoscopic Low Temperature Radiofrequency Plasma Surgery for Early Glottic Carcinoma |
| 投稿时间：2017-03-30 |
| DOI：10.11735/j.issn.1671-170X.2018.04.B012 |
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| 中文关键词: 支撑喉镜 低温射频等离子 声门型喉癌 并发症 发音功能 |
| 英文关键词:support laryngoscope low temperature radiofrequency plasma glottic carcinoma complications phonation function |
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| 中文摘要: |
| 摘 要：［目的］ 探讨支撑喉镜下低温射频等离子手术在早期声门型喉癌术中的应用效果。［方法］ 2012年2月到2016年1月选择在我院诊治的早期声门型喉癌患者132例为研究对象，根据随机信封抽签原则分为观察组与对照组各66例，对照组采用支撑喉镜下常规手术进行治疗，观察组采用支撑喉镜下低温射频等离子手术治疗，记录两组预后情况。［结果］ 两组均顺利完成手术，无术中严重并发症发生，两组手术时间比较差异无统计学意义(P>0.05)，观察组术中出血量与术后住院时间明显少于对照组(P<0.001，P=0.001)。观察组术后3个月的呼吸困难、黏膜水肿、发音功能损伤等并发症发生率为4.5%，对照组为19.7%，观察组明显低于对照组(χ2=4.882，P=0.001)。术后3个月观察组的基频微扰、振幅微扰值分别为0.28%±0.11%和1.43%±0.64%，均明显低于对照组的0.36%±0.21%和2.18%±0.19%(P均<0.001)，同时两组术后值均明显低于术前(P均<0.001)。两组的复发率、生存情况、颈部淋巴结及远处转移情况差异无统计学意义。［结论］支撑喉镜下低温射频等离子手术在早期声门型喉癌术中的应用具有更好的微创性，能减少术后并发症的发生，促进患者发音功能的恢复。 |
| 英文摘要: |
| Abstract：［Objective］ To investigate the efficacy of support laryngoscopic low-temperature radiofrequency plasma surgery for early glottic carcinoma. ［Methods］ One hundred and thirty two patients with early glottic carcinoma admitted from February 2012 to January 2016 were randomly assigned in two groups with 66 cases in each group：patients in study group received support laryngoscopic low-temperature radiofrequency plasma surgery and those in control group received conventional support laryngoscopic surgery. The efficacy and complications were observed and compared between two groups. ［Results］ All patients successfully completed surgery and there were no serious complications occurring during the operation. There was no significant difference in operation time between the two groups(P>0.05)，while the amount of intraoperative blood loss and the length of postoperative hospital stay in study group were significantly less than those in control group(P<0.001，P=0.001). Three months after surgery，the incidence rate of complications including dyspnea，mucosal edema and vocal function damage in study group was significantly lower than that in control group(4.5% vs. 19.7%，χ2=4.882，P=0.001). The fundamental frequency perturbation and amplitude perturbation values in two groups were significantly lower than the preoperative value(all P<0.001)，and those in study group were 0.28%±0.11% and 1.43%±0.64%，which were lower than those in control group(0.36%±0.21% and 2.18%±0.19%，all P<0.001). There were no significant differences in recurrence rate，survival condition，cervical lymph node and distant metastasis between two groups. ［Conclusion］ Laryngoscopic low-temperature radiofrequency plasma surgery is an effective minimally invasive procedure for early glottic carcinoma，which can reduce the incidence of postoperative complications，also promote recovery of vocal function for patients. |
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