| 李金国,宋西成.甲状腺癌相关信号传导通路的研究进展[J].肿瘤学杂志,2018,24(4):293-296. |
| 甲状腺癌相关信号传导通路的研究进展 |
| Research Progress of Thyroid Cancer Related Signaling Pathways |
| 投稿时间：2017-02-14 |
| DOI：10.11735/j.issn.1671-170X.2018.04.B001 |
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| 中文关键词: 甲状腺肿瘤 MAPK PI3K/AKT NF-κB |
| 英文关键词:thyroid cancer MAPK PI3K/AKT NF-κB |
| 基金项目:山东省重点研发计划（2015GSF118090）；山东省留学人员科技活动择优资助项目（鲁人社字2013-528号） |
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| 中文摘要: |
| 摘 要：甲状腺癌发生及发展的过程涉及多种信号传导通路，它们在肿瘤细胞的生长、增殖、凋亡过程中发挥重要作用。目前MAPK、PI3K/AKT、NF-κB信号传导通路为研究较为热门的甲状腺癌相关信号传导通路。全文对MAPK、PI3K/AKT及NF-κB信号传导通路在甲状腺癌中的作用作一综述，以期为甲状腺癌的治疗提供参考。 |
| 英文摘要: |
| Abstract：Thyroid cancer occurrence and development process involves multiple signaling pathways，These signaling pathways play an important role in the process of cell growth，proliferation and apoptosis. The MAPK，PI3K/AKT and NF-κB signaling pathways have became a hot topic of thyroid cancer related signaling pathways. The effect of MAPK，PI3K/AKT，NF-κB signaling pathways in thyroid cancer to provide reference for the treatment of thyroid cancer were summarized in this article. |
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