| 薛桂各,李胜泽.宫颈鳞癌患者202例盆腔淋巴结转移高危因素分析[J].肿瘤学杂志,2018,24(3):250-253. |
| 宫颈鳞癌患者202例盆腔淋巴结转移高危因素分析 |
| Analysis of Risk Factors of Pelvic Lymph Node Metastasis in 202 Patients with Cervical Squamous Cell Carcinoma |
| 投稿时间：2017-03-16 |
| DOI：10.11735/j.issn.1671-170X.2018.03.B015 |
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| 中文关键词: 宫颈癌 淋巴结转移 SCC-Ag |
| 英文关键词:cervical cancer lymph node metastasis SCC-Ag |
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| 摘要点击次数: 1689 |
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| 中文摘要: |
| 摘 要：［目的］ 探讨影响ⅠA ～ⅡB期宫颈鳞癌盆腔淋巴结转移的临床病理因素。［方法］ 回顾性分析接受宫颈癌根治性手术治疗的202例ⅠA～ⅡB期宫颈鳞癌患者的临床病理资料。［结果］ 盆腔淋巴结总阳性率为16.8%（34/202）。临床分期、肿瘤直径、宫颈间质浸润深度、生长方式、治疗前血SCC-Ag水平与宫颈癌盆腔淋巴结转移密切相关（P<0.05）；其中，治疗前血SCC-Ag水平（P=0.002）、宫颈间质浸润深度（P＝0.033）是影响ⅠＡ～ⅡＢ期宫颈鳞癌盆腔淋巴结转移的显著独立危险因素。治疗前血SCC-Ag的最佳预测值为3.05ng/ml。［结论］ 临床分期、肿瘤直径、宫颈间质浸润深度、生长方式、治疗前血SCC-Ag水平是ⅠＡ～ⅡＢ期宫颈鳞癌盆腔淋巴结转移的高危因素。 |
| 英文摘要: |
| Abstract：［Objective］ To investigate the clinical and pathological factors of pelvic lymph node metastasis in stage ⅠA ～ⅡB cervical squamous cell carcinoma. ［Methods］ The clinical and pathological data of 202 patients with stageⅠA ～ⅡB cervical squamous cell carcinoma treated with radical operation of cervical carcinoma were retrospectively analyzed.［Results］ The total positive rate of pelvic lymph nodes was 16.8%(34/202). Clinical stage，tumor diameter，the depth of cervical interstitial infiltration，growth pattern，and the level of SCC-Ag before treatment were closely related to cervical lymph node metastasis(P<0.05). Among them，t he level of SCC-Ag(P=0.002) and interstitial infiltration depth(P=0.033) were significant independent risk factors for pelvic lymph node metastasis of stage ⅠA ～ⅡB cervical squamous cell carcinoma. The best predictive value of SCC-Ag before treatment was 3.05ng/ml.［Conclusion］ Clinical stage，tumor diameter，cervical stromal invasion depth，growth pattern，SCC-Ag level before treatment are the high risk factors of pelvic lymph node metastasis in stage ⅠA ～ⅡB cervical squamous cell carcinoma． |
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