吴 兵,邵丽娜.乳酸及早期乳酸清除率对肿瘤相关复杂腹腔感染患者预后的评估价值[J].肿瘤学杂志,2018,24(1):55-57.
乳酸及早期乳酸清除率对肿瘤相关复杂腹腔感染患者预后的评估价值
Serum Lactate and Early Lactate Clearance Rate in Prognosis of Cancer Patients with Complicated Intra-Abdominal Infections
投稿时间:2017-01-04  
DOI:10.11735/j.issn.1671-170X.2018.01.B012
中文关键词:  乳酸  乳酸清除率  复杂腹腔感染
英文关键词:serum lactate  lactate clearance rate  complicated intra-abdominal infection
基金项目:
作者单位
吴 兵 中国医科大学附属第一医院 
邵丽娜 中国医科大学肿瘤医院辽宁省肿瘤医院 
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中文摘要:
      摘 要:[目的] 探讨乳酸及早期乳酸清除率对肿瘤相关复杂性腹腔感染患者预后的评估价值。[方法] 回顾性分析2011年10月至2015年9月期间的44例肿瘤相关复杂性腹腔感染患者的临床资料,依据28天是否存活分为死亡组(19例)和存活组(25例),比较两组患者的初始乳酸水平、早期乳酸清除率和急性生理与慢性健康评分Ⅱ( APACHEⅡ) 的差异。[结果] 死亡组患者的初始乳酸水平及APACHE Ⅱ评分均显著性高于存活组(P<0.05)。存活组患者的早期乳酸清除率高于死亡组(P<0.001)。[结论] 初始乳酸及早期乳酸清除率对肿瘤相关复杂性腹腔感染患者有重要价值,对判断预后有指导意义。
英文摘要:
      Abstract: [Objective] To assess the clinical value of serum lactate and early lactate clearance rate in the prognosis of cancer patients with complicated intra-abdominal infections. [Methods] Forty four cancer patients with complicated intra-abdominal infections patients admitted from October 2011 to September 2015 were retrospectively analyzed,among whom 19 died(fatal group) and 25 survived (survival group) in 28 days after admission.The initial serum lactate level,early lactate clearance rate and acute physical and chronic health evaluation Ⅱ(APACHEⅡ) score were compared between two groups. [Results] The initial serum lactate level and APACHEⅡ score were significantly lower and the early lactate clearance rate was significantly higher in the survival group than those in the fatal group(P<0.001). [Conclusion] Initial serum lactate level and early lactate clearance rate shows a predictive value for prognosis in cancer patients with complicated intra-abdominal infections.
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