| 冯 娜,杨 琛,潘蔚芸.声触诊组织成像与定量技术对甲状腺结节性质的诊断价值分析[J].肿瘤学杂志,2017,23(12):1102-1106. |
| 声触诊组织成像与定量技术对甲状腺结节性质的诊断价值分析 |
| Diagnostic Value of Virtual Touch Tissue Imaging Quantification in Thyroid Nodules |
| 投稿时间：2017-06-30 |
| DOI：10.11735/j.issn.1671-170X.2017.12.B011 |
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| 中文关键词: 声触诊组织成像与定量技术 甲状腺结节 诊断价值 |
| 英文关键词:virtual touch tissue imaging quantification thyroid nodules diagnostic value |
| 基金项目:浙江省医药卫生科技计划项目(2015KYB057）；浙江省科技计划项目（ 2017C37090） |
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| 中文摘要: |
| 摘 要： ［目的］ 分析声触诊组织成像与定量技术（virtual touch tissue imaging quantification，VTIQ）对甲状腺结节性质的诊断价值。［方法］ 选取2016年8月至2017年3月间收治行甲状腺手术的甲状腺结节患者105例作为研究对象，甲状腺结节共计149颗。先后行VTIQ与手术切除后病理活检，分析VTIQ的诊断价值。［结果］ 105例患者共取得甲状腺结节149颗，其中良性44颗，恶性105颗。甲状腺良恶性结节患者的性别、年龄、体重指数、甲状腺大小无统计学差异（P>0.05），而良恶性结节的血流、边界、内部回声、纵横比、钙化相比较具有统计学意义（P<0.05）。良性结节的SWV最小值、最大值、平均值分别为2.32±0.62m/s、3.02±0.92m/s、2.71±0.76m/s，均明显低于恶性结节值（P<0.05）。各结节中SWV最小值、最大值、平均值对应的ROC曲线面积分别为0.849、0.792和0.837。以SWV平均值诊断效能最佳，其截断值为3.04m/s。VTIQ诊断甲状腺结节性质的敏感度为81.81%、特异性为97.14%、准确率为92.61%。VTIQ检测的敏感度、特异性、准确率均高于常规超声的相应值（P<0.05）。［结论］ VTIQ判断甲状腺良恶性结节的敏感度、特异性、准确率均较好，是一种无创、易行、可靠的检查方法，具有很好的临床使用价值。 |
| 英文摘要: |
| Abstract：［Objective］ To evaluate the diagnostic value of virtual touch tissue imaging quantification (VTIQ) on thyroid nodules. ［Methods］ A total of 105 patients underwent thyroid surgery from August 2016 to March 2017 with 149 thyroid nodules were enrolled. VTIQ and postoperative biopsy were made to analysis of VTIQ diagnostic value. ［Results］ Total 149 thyroid nodules were found from 105 patients，44 thyroid nodules were benign and the rest were malignant. There were no statistically siginificant difference between benign and malignant thyroid nodules in the aspact of patient gender，age，body mass index，thyroid size，while blood flow，boundary，internal echo，calcification，aspect ratio had a statistically significant difference between benign and malignant thyroid nodules. The minimum，maximum，and average value of SWV for benign nodules were 2.32±0.62m/s，3.02±0.92m/s and 2.71±0.76m/s，respectively，which were significantly lower than those of malignant nodules(P<0.05). ROC curve area of the minimum，maximum，and average values of SWV in each nodule were 0.849，0.792，0.837. The diagnostic effectiveness of the SWV average was best with a cutoff of 3.04m/s. The sensitivity of VTIQ was 81.81%，the specificity was 97.14% and the accuracy was 92.61%. VTIQ detection had a statistically significant higher sensitivity，specificity and accuracy than conventional ultrasound.［Conclusions］ Sensitivity，specificity，accuracy of VTIQ on distinguishing the benign and malignant nodules are rather good，and is a noninvasive，easy and reliable inspection methods. It has a good clinical value. |
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