卢 锦,史著俊,王金华.宫颈神经内分泌癌30例临床分析[J].肿瘤学杂志,2017,23(11):996-999.
宫颈神经内分泌癌30例临床分析
Neuroendocrine Cervix Carcinoma:A Clinical Analysis of 30 Cases
投稿时间:2016-12-11  
DOI:10.11735/j.issn.1671-170X.2017.11.B011
中文关键词:  宫颈癌  神经内分泌癌  小细胞癌  大细胞癌
英文关键词:cervical cancer  neuroendocrine cervix carcinoma  small cell carcinoma  large cell carcinoma
基金项目:
作者单位
卢 锦 江苏省肿瘤医院南京医科大学附属肿瘤医院 
史著俊 江苏省肿瘤医院南京医科大学附属肿瘤医院 
王金华 江苏省肿瘤医院南京医科大学附属肿瘤医院 
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中文摘要:
      摘 要:[目的] 探讨宫颈神经内分泌癌的诊断、治疗和预后因素。[方法] 回顾性分析2011年1月至2015年12月南京医科大学附属肿瘤医院收治的30例宫颈神经内分泌癌患者的临床资料。[结果] 分期、淋巴结转移、血清神经元特异性烯醇化酶水平与总生存时间密切相关(P<0.05),而肿瘤浸润深度、脉管内癌栓、肿瘤直径、治疗方式对总生存时间无明显影响(P>0.05)。[结论]宫颈神经内分泌癌是一种罕见的妇科恶性肿瘤,预后差。分期、淋巴结转移能够影响预后。血清神经元特异性烯醇化酶水平能够作为监测预后的指标。
英文摘要:
      Abstract:[Objective] To analyze the diagnosis,treatment and prognosis of cervical neuroendocrine carcinoma.[Methods] The clinical data of 30 patients with cervical neuroendocrine carcinoma admitted in Nanjing Medical University Affiliated Jiangsu Cancer Hospital between January 2011 and December 2011 were retrospective analyzed. [Results] The clinical stages,lymph node metastasis,serum neuron specific enolization enzyme levels were closely related to the overall survival time(P<0.05),while the tumor infiltration depth,vascular tumor emboli,tumor diameter,treatment had no significant impact on overall survival time(P>0.05). [Conclusion] Neuroendocrine cervical carcinoma is a rare form of gynecological malignant tumor with poor prognosis. Stages,lymph node metastasis may affect the prognosis,serum neuron specific enolization enzyme levels may be one of the indicators of prognosis.
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