| 费 倩,尹 丽,何 侠.结外NK/T细胞淋巴瘤预后模型的研究进展[J].肿瘤学杂志,2017,23(9):816-820. |
| 结外NK/T细胞淋巴瘤预后模型的研究进展 |
| Progress in Prognostic Models of Extranodal Natuaral Killer/T Cell Lymphoma |
| 投稿时间：2017-02-23 |
| DOI：10.11735/j.issn.1671-170X.2017.09.B016 |
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| 中文关键词: 结外ＮＫ/Ｔ细胞淋巴瘤 预后模型 PINK |
| 英文关键词:extranodal natural killer/t-cell lymphoma prognostic model prognostic index for natural killer/T cell lymphoma |
| 基金项目:江苏省科技厅临床医学重点专项（BL2014091） |
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| 中文摘要: |
| 摘 要：结外NK/T细胞淋巴瘤(extranodal natural killer/T-cell lymphoma，ENKTCL)是一种EB病毒相关的、具有高度侵袭性的非霍奇金淋巴瘤，晚期患者预后差。以非蒽环类药物为基础的联合治疗方案相比传统的蒽环类药物化疗方案，显著性改善了患者生存。回顾了目前已提出的ENKTCL预后模型，分析表明基于蒽环类化疗方案获得的预后模型将面临淘汰，而新型预后模型的提出将有助于更好地区分患者，进一步指导临床医生制定相应的治疗策略。 |
| 英文摘要: |
| Abstract：Extranodal natural killer/T-cell lymphoma (ENKTCL) is an EBV-associated and highly aggressive non-Hodgkin lymphoma，with poor prognosis in advanced patients. Non-anthracycline-based therapy significantly improves survival compared with traditional anthracycline-containing regimens. The prognostic models of ENKTCL proposed are reviewed in this article. It indicates that the prognostic models based on anthracycline -containing regimens might be eliminated. In contrast，the new prognostic models could be used to discriminate patients better so as to help clinicians formulate risk-adapted treatment approaches. |
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