| 曹卓一,邓九零,方明笋.大肠癌无创早期诊断的核酸检测技术研究进展[J].肿瘤学杂志,2017,23(8):707-710. |
| 大肠癌无创早期诊断的核酸检测技术研究进展 |
| Research Progress of Nucleic Acid Detection Techniques in Noninvasive Early Diagnosis of Colorectal Cancer |
| 投稿时间：2016-11-17 |
| DOI：10.11735/j.issn.1671-170X.2017.08.B012 |
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| 中文关键词: 大肠癌 无创早期诊断 核酸检测 |
| 英文关键词:colorectal cancer noninvasive early diagnosis nucleic acid detection |
| 基金项目:浙江省医药科技计划项目(2017KY565) |
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| 摘要点击次数: 1623 |
| 全文下载次数: 480 |
| 中文摘要: |
| 摘 要：大肠癌无创早期诊断有利于提高患者的生存率和顺应性，对粪便和血液中人源核酸进行检测是大肠癌无创早期诊断的重要途径，具有高特异性、高灵敏度和适用于大规模人群筛查等优点。核酸检测技术包括DNA检测技术和RNA检测技术，全文就这两类核酸检测技术应用于大肠癌早期无创诊断的研究进展进行概述。 |
| 英文摘要: |
| Abstract：Noninvasive early diagnosis of colorectal cancer is beneficial to improve the survival rate and compliance of patients. Detection of nucleic acid molecules in stool and blood is a noninvasive method for early diagnosis of colorectal cancer with the advantages of high specificity and high sensitivity，which can be used in population screening. This article reviews the research advances on detection techniques of nucleic acids，including DNA detection and RNA detection，and their applications in the future. |
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