| 郭 坤,黄 勇,李云波.18F-FDG PET/CT显像特征与恶性淋巴瘤病理类型的相关性[J].肿瘤学杂志,2017,23(6):479-482. |
| 18F-FDG PET/CT显像特征与恶性淋巴瘤病理类型的相关性 |
| 18F-FDG PET/CT Imaging Features in Different Pathological Types of Malignant Lymphoma |
| 投稿时间：2016-12-17 |
| DOI：10.11735/j.issn.1671-170X.2017.06.B005 |
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| 中文关键词: 淋巴瘤 病理分型 18F-FDG PET/CT |
| 英文关键词:lymphoma pathological subtype 18F-FDG PET/CT |
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| 中文摘要: |
| 摘 要：［目的］ 探讨18F-FDG PET/CT显像特征与恶性淋巴瘤病理类型的关系。［方法］ 回顾性入组2013年1月至2016年6月18F-FDG PET/CT显像考虑为淋巴瘤可能的74例患者（男性41例，女性33例），穿刺、手术病理明确最终诊断。分析18F-FDG PET/CT诊断与病理诊断一致性。同时探讨PET/CT显像特征如是否伴脾大、结外侵犯、浅表及深部淋巴结累及、SUVmax等与病理类型的相关性。［结果］ 74例18F-FDG PET/CT考虑为淋巴瘤可能的患者中，最终病理明确为淋巴瘤者占70.27%（52/74），淋巴瘤SUVmax明显高于非淋巴瘤（10.68±4.49 vs 5.04±2.63，t=-5.490，P=0.001），其中HD占25.00%（13/52），NHL占75.00%（39/52）。HD组发病年龄小于NHL组（P=0.001）；18F-FDG PET/CT 显像HD组累及深部淋巴结及结外器官与NHL组相比，差异均有统计学意义（P=0.031，P=0.013）；浅表淋巴结累及组间差异无统计学意义。NHL组SUVmax高于HD组（11.47±4.86 vs 8.55±2.29，Z=-2.188，P=0.029）。［结论］ 不同病理类型淋巴瘤18F-FDG PET/CT显像特征不同，其中弥漫大B细胞淋巴瘤累及范围广泛，NK/T细胞淋巴瘤以累及鼻腔多见。 |
| 英文摘要: |
| Abstract：［Objective］ To examine the characteristics of 18F-FDG PET/CT findings in different pathologic types of malignant lymphoma. ［Methods］ Seventy four patients(41 males，33 females) with suspected malignant lymphoma on 18F-FDG PET/CT imaging underwent biopsy and pathologic examination from January 2013 to June 2016. The features of PET/CT imaging in different pathological types of lymphoma were analyzed. ［Results］ Fifty two patients were diagnosed as malignant lymphoma by pathological examination(70.27%)，including 13 cases of Hodgkin’s disease(HD) and 39 cases of non-Hodgkin’s lymphoma(NHL). The maximum standard uptake value(SUVmax) was significantly higher in lymphoma patients than that in non-lymphoma patients(10.68±4.49 vs 5.04±2.63，t=-5.490，P=0.001). Compared to the NHL，the age of HD patients was significantly lower（P=0.001）. There was significant difference in the involvement of external organs and deep lymph nodes between two groups(P=0.031，P=0.013），but no difference in superficial lymph node involvement. SUVmax was higher in NHL group than that in HD group(11.47±4.86 vs 8.55±2.29，Z=-2.188，P=0.029). ［Conclusion］ The features 18F-FDG PET/CT imaging in Hodgkin’s lymphoma are different from those in non-Hodgkin’s lymphoma. |
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