| 卢 霞,孟晶晶,柏 江.18F-FDG PET/CT在心脏肿瘤诊断的临床应用价值[J].肿瘤学杂志,2017,23(6):474-478. |
| 18F-FDG PET/CT在心脏肿瘤诊断的临床应用价值 |
| Clinical Application of 18F-FDG PET/CT in Diagnosis of Cardiac Neoplasm |
| 投稿时间：2017-03-18 |
| DOI：10.11735/j.issn.1671-170X.2017.06.B004 |
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| 中文关键词: 心脏肿瘤 18F-FDG PET/CT 鉴别诊断 |
| 英文关键词:heart neoplasms 18F-FDG PET/CT noninvasive differential diagnosis |
| 基金项目:国家自然科学基金（81641072）；北京市医院管理局“青苗”计划（QML20150605）；北京市优秀人才（2015000021469G197） |
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| 中文摘要: |
| 摘 要：［目的］ 评价18F-FDG PET/CT在心脏肿瘤诊断中的临床应用价值。［方法］ 回顾性分析自2014年10月至2017年3月在首都医科大学附属北京安贞医院行18F-FDG PET/CT全身显像的心脏肿瘤患者共27例，患者最终诊断以手术病理结果或随访结果为依据。18F-FDG PET/CT影像心脏占位病变可见明显异常FDG浓聚灶，SUVmax≥5.7判断为恶性病变可能大，并与最终诊断结果进行比较，分析18F-FDG PET/CT在心脏占位性病变良恶性的鉴别能力。采用两样本t检验分析数据。［结果］ 27例心脏肿瘤患者中，恶性11例，良性占位16例。18F-FDG PET/CT显像，恶性占位（n=11）平均SUVmax 9.03±4.5（2.0～15.9）明显高于良性心脏占位性病变（n=16）平均SUVmax 3.25±2.51（0.6～10.2），差异有统计学意义（t=4.25，P<0.001）。将SUV≥5.7作为恶性诊断的阈值，18F-FDG PET/CT诊断心脏恶性肿瘤的灵敏度81.8% （9/11），特异性93.8%（15/16），准确率88.9%（24/27）。［结论］ 全身18F-FDG PET/CT检查对心脏肿瘤，特别是原发性心脏肿瘤良恶性诊断有重要的临床价值。 |
| 英文摘要: |
| Abstract：［Objective］ To evaluate the clinical value of 18F-FDG PET/CT in the diagnosis of cardiac neoplasm.［Methods］ From October 2014 to March 2017，a total of 27 patients diagnosed with cardiac neoplasm underwent whole body 18F-FDG PET/CT imaging were respectively analysised. 18F-FDG PET/CT diagnosis was confirmed by either histopathology or the follow-up outcome. Cardiac space-occupying lesions shows increased FDG uptake in the imaging of PET/CT and diagnosed malignance lesions when SUVmax≥5.7. Then compared with histopathology or the follow-up outcome to evaluate the clinical application of 18F-FDG PET/CT imaging in the diagnosis of cardiac neoplasm. Two-sample t test was used for data analysis. ［Results］ Among 27 cases of cardiac space-occupying lesions，11 cases were malignant tumors，16 cases were benign tumors. The average SUVmax of malignant tumors (n=11) was 9.03±4.5，which was significantly higher than that of benign tumors(n=16，3.25±2.51)（t=4.25，P<0.001）. With a cut-off SUVmax≥ 5.7，18F-FDG PET/CT could be used to diagnose cardiac neoplasm with a sensitivity of 81.8% （9/11），specificity of 93.8%（15/16），and accuracy of 88.9%（24/27）. ［Conclusion］ The whole body scan of 18F-FDG PET/CT can aid the noninvasive diagnosis of cardiac malignant tumors from benign lesions. |
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