| 杨 海,陈 盈,李 欣.CT值鉴别纯磨玻璃密度的肺原位腺癌与微浸润腺癌的价值[J].肿瘤学杂志,2017,23(2):121-124. |
| CT值鉴别纯磨玻璃密度的肺原位腺癌与微浸润腺癌的价值 |
| The CT Value in Differentiating Lung Adenocarcinoma in Situ(AIS) with Minimally Invasive Adenocarcinoma(MIA) Manifesting as Pure Ground-glass Opacity |
| 投稿时间：2016-08-02 |
| DOI：10.11735/j.issn.1671-170X.2017.02.B009 |
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| 中文关键词: 肺肿瘤 原位腺癌 微浸润腺癌 体层摄影术，X线计算机 |
| 英文关键词:lung neoplasms lung adenocarcinoma in situ minimally invasive adenocarcinoma Tomography,X-ray computed |
| 基金项目:浙江省台州市科技局A类项目（14SF03）；浙江省自然科学基金（LY13H180010）；浙江省医药卫生基金（2013KYA223） |
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| 中文摘要: |
| 摘 要：［目的］ 探讨平扫CT值对表现为纯磨玻璃密度的肺原位腺癌（AIS）和微浸润腺癌（MIA）的鉴别诊断价值。［方法］ 回顾性分析表现为纯磨玻璃密度的肺原位腺癌32例、微浸润腺癌45例的术前资料，比较两组病例平扫CT值，并通过ROC曲线确定两组病例CT值的最佳截断点。［结果］ 原位腺癌与微浸润腺癌的CT值不同（-595.37±79.49Hu vs -497.62±121.08Hu；Z=-3.406，P<0.05），CT值对于原位腺癌与微浸润腺癌的诊断价值较好（曲线下面积0.729，95%CI：0.618~0.839，P<0.05），-491.55Hu为AIS与MIA的最佳CT值截断点（灵敏度为48.9%，特异性为93.7%）。［结论］ 平扫CT值对于肺原位腺癌和微浸润腺癌的诊断有一定指导意义，当CT值＞-491.55Hu时，病灶为MIA可能性大；当CT值＜-491.55Hu时，病灶为AIS可能性大。 |
| 英文摘要: |
| Abstract：［Objective］ To explore the CT value in differentiating lung adenocarcinoma in situ(AIS) with minimally invasive adenocarcinoma(MIA) manifesingt as pure ground-glass opacity，and to provide guidance for the diagnosis of AIS and MIA. ［Methods］ The preoperative CT data of 32 AIS and 45 MIA were analyzed retrospectively，compared their plain scan CT value，and found the best cut-off on ROC curve in the two groups. ［Results］ The CT value between AIS and MIA was different（-595.37±79.49Hu vs -497.62±121.08Hu，Z=-3.406，P<0.05），the CT value was a good indicator to distinguish AIS and MIA(area under the ROC was 0.729，95%CI：0.618～0.839，P<0.05)，and the CT value of -499.51Hu was the best cut-off for AIS and MIA(sensitivity was 48.9%，specificity was 93.7%). ［Conclusion］ The CT value may be benefit to diagnosis the lung adenocarcinoma in situ(AIS) and minimally invasive adenocarcinoma(MIA) which manifested as pure ground-glass opacity.The lesion’CT value bigger than -499.51Hu is more likely to be MIA；while the lesion’CT value smaller than -499.51Hu is more likely to be AIS. |
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