| 郭 坤,黄 勇,魏熠鑫.18F-FDG PET/CT 在不明原因发热患者中对淋巴瘤的筛查价值[J].肿瘤学杂志,2017,23(2):116-120. |
| 18F-FDG PET/CT 在不明原因发热患者中对淋巴瘤的筛查价值 |
| 18F-FDG PET/CT for Screening of Lymphoma in Patients with Fever of Unknown Origin |
| 投稿时间：2016-08-18 |
| DOI：10.11735/j.issn.1671-170X.2017.02.B008 |
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| 中文关键词: 不明原因发热 淋巴瘤 18F-FDG PET/CT |
| 英文关键词:fever of unknown origin lymphoma 18F-FDG PET/CT |
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| 中文摘要: |
| 摘 要：［目的］ 探讨18F-FDG PET/CT显像在不明原因发热患者（fever of unknown origin，FUO）中筛查淋巴瘤的价值。［方法］ 回顾18F-FDG PET/CT显像考虑为淋巴瘤可能的36例FUO患者资料，分析比较18F-FDG PET/CT检查结果与最终诊断。同时记录患者基本信息包括年龄、性别及发热持续时间；体格检查包括最高体温及热度；实验室检查包括白细胞、中性粒百分比、血小板、血红蛋白、ESR、CRP、PCT等；组间差异比较采用t检验或卡方检验。［结果］ 36例18F-FDG PET/CT考虑为淋巴瘤可能的患者中，最终病理明确为淋巴瘤者20例，占55.6%（20/36）。与非淋巴瘤组相比，淋巴瘤患者SUVmax显著升高（9.02±4.03 vs 4.94±2.71，t=3.466，P=0.001）。根据患者最高体温分为中度热、高热及超高热，组间发热程度差异有统计学意义（χ2=8.23，P=0.016）。与淋巴瘤组患者相比，非淋巴瘤组患者发热持续时间更长。而年龄、性别、伴随症状、体征及实验室检查在两组间差异无统计学意义（P均>0.05）。［结论］ 18F-FDG PET/CT显像对淋巴瘤有一定的诊断价值。病灶SUVmax值、患者发热程度及发热持续时间对FUO中淋巴瘤的筛查提供重要参考。 |
| 英文摘要: |
| Abstract：［Objective］ To evaluate the application of 18F-FDG PET/CT for screening of lymphoma in patients with fever of unknown origin(FUO). ［Methods］ Clinical data of 36 patients with FUO undergoing 18F-FDG PET/CT examination were retrospectively reviewed. The results were compared with final diagnosis based on the biopsy，surgical pathology or clinical follow-up. Basic information of patients including age，gender，degree and duration of fever，physical examination，white blood count，percentage of neutrophils，platelet count，hemoglobin，ESR，CRP and PCT were recorded. ［Results］ Among 36 FUO patients，20(55.6%) were diagnosis as lymphoma by 18F-FDG PET/CT. Compared with the non-lymphoma patients，SUVmax was higher in lymphoma patients(9.02±4.03 vs 4.94±2.71，t=3.466，P=0.001). Non-lymphoma patients had a longer duration of fever. ［Conclusion］ 18F-FDG PET/CT is a valuable imaging technique for screening lymphoma in FUO patients，SUVmax，degree and duration of fever may provide important information for screening. |
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