| 黎 旦,宾石珍,程品晶.AXB算法与AAA算法在直肠癌VMAT放射治疗中的剂量学差异[J].肿瘤学杂志,2017,23(2):92-96. |
| AXB算法与AAA算法在直肠癌VMAT放射治疗中的剂量学差异 |
| Dosimetry Differences Between Acuros External Beam Algorithm and Anisotropy Analysis Algorithm in Radiotherapy for the VMAT Plan of Rectal Cancer |
| 投稿时间：2016-06-20 |
| DOI：10.11735/j.issn.1671-170X.2017.02.B003 |
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| 中文关键词: AXB算法 AAA算法 直肠肿瘤 剂量学 剂量验证 |
| 英文关键词:AXB algorithm AAA algorithm rectal neoplasms dosimetric verification |
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| 中文摘要: |
| 摘 要：［目的］ 比较AXB算法与AAA算法在直肠癌VMAT放射治疗中的剂量学差异，并进行剂量验证。［方法］ 随机选取40例直肠癌患者定位CT影像资料，采用VMAT双弧方式设计放射治疗计划。比较两种算法的剂量体积直方图、靶区、危及器官和正常组织的剂量、机器跳数、验证通过率和计算时间。［结果］ 靶区：95％靶体积受到的剂量（D95%）和最大剂量（Dmax）两种算法间差异无统计学意义 (P>0.05)，平均剂量（Dmean）AXB算法高于AAA算法(P<0.05)，最小剂量（Dmin）AAA算法高于AXB算法（P<0.05）；小肠：Dmean与D50%差异无统计学意义(P>0.05)，Dmin：AAA算法高于AXB算法（P<0.05），Dmax：AXB算法高于AAA算法(P<0.05)；膀胱：Dmin、Dmean与D50%差异无统计学意义(P>0.05)，Dmax：AXB算法高于AAA算法(P<0.05)；双侧股骨头：Dmin和Dmax差异无统计学意义(P>0.05)，Dmean：AAA算法高于AXB算法(P<0.05)，D5%：AAA算法高于AXB算法（P<0.05）；通过率：两种算法差异无统计意义（P>0.05）。［结论］ 在直肠癌VMAT计划中两种算法剂量学上存在一定差异，但都满足剂量学和临床要求，且在验证通过率方面差异无统计学意义，两种算法都可以应用于临床治疗。 |
| 英文摘要: |
| Abstract：［Objective］ To compare the dosimetry differences between acuros external beam (Acuros XB) algorithm and anisotropy analysis algorithm(AAA) in the VMAT plan of rectal cancer. ［Methods］：Forty rectal cancer patients were randomly selected，with volumetric modulated arc therapy(VMAT) with double arcs were respectively designed for each patient. The dosimetry differences of target volumes and organs at risk(OARs) isodose distribution，monitor units (MUs) and calculate time and dose pass rate were compared in the two algorithm.［Results］Target：there was no significant difference between those two algorithm in dose received by 95% of target volumes(D95%) (P>0.05)and the max dose(Dmax)，but the mean dose(Dmean) the AXB was higher than AAA(P<0.05)，however the min dose(Dmin) was opposite；Small intestine：there was no significant difference between in Dmean and D50，but the Dmax AXB was higher than AAA(P<0.05)，the Dmin was opposite；Bladder：there was no significant difference among in Dmean，D50% and Dmin，the Dmax AXB was higher than AAA(P<0.05)；Femoral head：there was no significant difference between in Dmin and Dmax，the Dmean and D5% AAA was higher than AXB(P<0.05). There was no significant difference between in dose pass rate. ［Conclusion］ There are some difference in the VMAT plan of rectal cancer with Acuros XB algorithm and AAA algorithm，but all the dose indexes of these two algorithms meet the clinical requirement，so both the two algorithms can be clinically applied. |
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