| 廖光星,李 宁,廖 宁.分化型甲状腺癌术后患者131I治疗的辐射防护初探[J].肿瘤学杂志,2016,22(11):888-892. |
| 分化型甲状腺癌术后患者131I治疗的辐射防护初探 |
| Radiation Protection of Postoperative 131I Treatment for Patients with Differentiated Thyroid Cancer |
| 投稿时间：2016-05-27 |
| DOI：10.11735/j.issn.1671-170X.2016.11.B004 |
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| 中文关键词: 甲状腺肿瘤 131I治疗 辐射防护 |
| 英文关键词:thyroid neoplasms 131I treatment radiation protection |
| 基金项目:广西医药卫生自筹经费计划课题（Z2015585 、Z2015695、Z2016472、Z2016498）、广西教育厅2016年中青年教师基础能力提升项目（KY2016LX025、KY2016LX050）和2016 年度广西高等教育本科教学改革工程立项项目（2016JGB186）、广西医科大学教育教学改革课题（2015XJGB23、2016XJGA21）和2014年广西医科大学青年基金课题（GXMUYSF201408） |
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| 中文摘要: |
| 摘 要：［目的］ 通过测定碘-131(131I)治疗分化型甲状腺癌(DTC)患者体外辐射水平和有关人员受照剂量，探讨131I治疗过程中的辐射防护方法，使得在临床治疗过程中将辐射危害降到合理的最低水平。［方法］ 选择DTC术后行131I治疗的患者10例及其陪同人员作为研究对象。患者服药后，用451P-DE-S1-YGG型电离室巡测仪测量即时、24h、72h、5d及7d不同时间点距患者5cm、50cm、100cm及200cm处的剂量当量率水平，用个人剂量测量30d内的个人剂量，采用谱仪测量服药室内空气中131I的活度水平。［结果］ 服药即刻患者周围辐射剂量值非常高，可达2000μSv/h，5d后200cm处的辐射剂量率均小于5μSv/h；甲癌患者的个人剂量水平为26.78~61.96(46.25±11.58)mSv，陪同人员的个人剂量水平中位数为0.35(0.29~0.43)mSv；服药室空气中131I的活度水平为42.6Bq/m3，工作人员每年因吸入131I所致的有效剂量为0.019mSv。［结论］ 甲状腺癌患者在行131I治疗的过程中其周围具有较高的辐射剂量水平，应提高工作人员、患者和陪同人员的辐射防护意识，减少不必要的照射。 |
| 英文摘要: |
| Abstract：［Objective］ To investigate the radiation protection of postoperative 131I therapy in patients with differentiated thyroid carcinoma (DTC). ［Methods］ Ten DTC patients with postoperative 131I treatment，accompanying persons and relevant hospital staff were included in this study. The dose equivalent rate in various distance and times after treatment was measured by 451P-DE-S1-YGG ionization chamber survey instrument；the personal dose within 30 days was measured by personal dose agent；the 131I activity in the medicine chamber was measured by gamma spectrometer. ［Results］ The dose of radiation were reachable 2000μSv/h after taking the medicine immediately. After 5μSv/h days，the radiation dose rate were less than 5 in the distance of 200cm from the patients. The dose of DTC patients were 26.78~61.96(46.25±11.58)mSv and their accompanying persons were 0.35(0.29~0.43)mSv. The 131I activity in the medicine chamber were 42.6Bq/m3，the effective dose of the hospital staff was 0.019mSv. ［Conclusion］ There is high dose radiation in the 131I treatment process，and it is necessary to reduce the exposure of radiation for accompanying people and relevant hospital staff. |
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