| 赵 靖,王荣福.血清Tg水平在分化型甲状腺癌诊疗进程中的临床价值[J].肿瘤学杂志,2016,22(11):880-884. |
| 血清Tg水平在分化型甲状腺癌诊疗进程中的临床价值 |
| The Clinical Value of Serum Thyroglobulin in the Management of the Patients with Differentiated Thyroid Carcinoma |
| 投稿时间：2016-06-18 |
| DOI：10.11735/j.issn.1671-170X.2016.11.B002 |
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| 中文关键词: 血清Tg 甲状腺肿瘤 复发转移 |
| 英文关键词:serum thyroglobulin thyroid neoplasms recurrence and metastases |
| 基金项目:国家重大科学仪器设备开发专项（2011YQ03011409）；十二五国家支撑项目基金（2014BAA03B03） |
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| 中文摘要: |
| 摘 要：大多数分化型甲状腺癌（DTC）分化良好，复发及转移率低，预后较好，但部分亚型分化不良，容易复发并发生局部及远处转移，死亡率较高。大量研究表明血清Tg水平可作为监测分化型甲状腺癌术后复发及转移的特异性指标。由于各种良、恶性甲状腺疾病都可导致血清Tg水平升高，以往认为术前监测血清Tg水平的意义不大，但近年来越来越多的研究表明，术前血清Tg水平的监测也具有重要的临床价值。本文旨在对近年来关于甲状腺球蛋白（Tg）在DTC术前及术后诊疗过程中的应用进展进行综述。 |
| 英文摘要: |
| Abstract：The vast majority of differentiated thyroid cancer(DTC) are well-differentiated，with a low rate of recurrence and metastasis，and the prognosis are usually excellent.However，a small amount of subtypes are poorly differentiated tumors with a high incidence of recurrence and loco-regional and distant metastases，which lead to a lower rate of survival. Multiple studies have confirmed serum thyroglobulin as the specific predictor of persistent or recurrent disease. Serum Tg levels can be elevated in most thyroid diseases，including benign or meligant ones.Therefore，it may be once supposed to have little significance to monitor preoperative serum Tg level. In recent years，a series of studies have suggested the clinical value of serum thyroglobulin both in the preoperative and postoperative stages.This article aims to summarize the progress in serum thyroglobulin for the management of differentiated thyroid cancer. |
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