| 卜珊珊,王修身,丁丹红.49例原始神经外胚层肿瘤临床特征及生存分析[J].肿瘤学杂志,2016,22(9):742-745. |
| 49例原始神经外胚层肿瘤临床特征及生存分析 |
| Clinical Features and Survival Analysis of 49 Cases with Primitive Neuroectodermal Tumor |
| 投稿时间：2016-01-03 |
| DOI：10.11735/j.issn.1671-170X.2016.09.B011 |
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| 中文关键词: 原始神经外胚层肿瘤 临床特征 预后 |
| 英文关键词:primitive neuroectodermal tumor clinical features prognosis |
| 基金项目: |
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| 中文摘要: |
| 摘 要：［目的］ 探讨影响原始神经外胚层肿瘤预后的相关因素。［方法］ 回顾性分析了49例原始神经外胚层肿瘤患者的临床资料及预后相关因素。［结果］ 49例原始神经外胚层肿瘤的1年、2年、3年、5年生存率分别为65.3%、51.0%、26.5%、8.4%、中位生存时间为16个月；单因素分析显示年龄、肿块大小、分期、治疗方式是影响原始神经外胚层肿瘤患者预后的重要因素。Cox多因素分析后发现肿瘤分期和治疗方式是影响其预后的独立危险因素。［结论］ 原始神经外胚层肿瘤采用联合放疗的综合治疗方案有助于改善患者的预后。 |
| 英文摘要: |
| Abstract：［Objective］ To analyze the clinical features and survival of patients with primitive neuroectodermal tumor（PNET）.［Methods］ Clinical data of 49 patients with PNET admitted in Henan Provincial Cancer Hospital from January 2002 to December 2012 were analyzed retrospectively. ［Results］ The 1-，2-，3-，5-year survival rates of PNET patients were 65.3%，51.0%，26.5%，8.4%，respectively，with median survival time 16 months. Univariate analysis revealed that age，tumor size，TNM and treatment modality were significantly correlated with the survival of patients，and multivariate analysis indicated that TNM and treatment modality were independent prognostic factors for PNET. ［Conclusion］ Comprehensive treatment modality containing radiotherapy may benefit the prognosis of patients with PNET. |
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