| 冯 玺,吴德全,彭 珂.Tomo治疗多发性骨转移单计划多靶区与多计划单靶区配准的对比[J].肿瘤学杂志,2016,22(8):663-666. |
| Tomo治疗多发性骨转移单计划多靶区与多计划单靶区配准的对比 |
| Comparison Between Single-plan with Multi-target and Multi-plan with Single-target in Tomotherapy in the Treatment of Multiple Bone Metastases |
| 投稿时间：2015-08-06 |
| DOI：10.11735/j.issn.1671-170X.2016.08.B011 |
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| 中文关键词: Tomotherapy 多发性骨转移 放射治疗 配准精度 |
| 英文关键词:Tomotherapy multiple bone metastases radiotherapy registration accuracy |
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| 中文摘要: |
| 摘 要：［目的］ 探讨Tomotherapy图像引导下多发性骨转移治疗中的单计划多靶区（A组）与多计划单靶区（B组）的配准精确度对比。［方法］ 采集在Tomotherapy治疗的15例多发性骨转移患者分次治疗中的配准数据，其中单计划多靶区患者（A组）8例，多计划单靶区患者（B组）7例。每次放疗前行MVCT扫描，均采用Bone Technique(骨性技术)为配准条件并结合人工校对，通过统计学软件的运用分析比较患者分次治疗中左右(X轴)、头脚(Y轴)、上下(Z轴)、旋转(Roll)方向的配准误差值。［结果］ A组8例共200次在线配准数据与B组7例175次在线配准数据对比，摆位绝对误差只有在头脚方向（Y轴）A组大于B组，分别为(5.24±4.01)mm、(3.72±3.67)mm(P=0.041)。摆位相对误差只有在左右方向（X轴）A组大于B组，分别为（2.81±2.07）mm、（1.87±1.83）mm（P=0.008）。［结论］ 两种计划方法对多发性骨转移分次放疗的配准精度各有优劣，但均在可控范围内，可根据临床实际选用合适的计划方法。 |
| 英文摘要: |
| Abstract：［Objective］ To study the comparison of registration accuracy between single-plan with multi-target(group A) and multi-plan with single-target(group B) in Tomotherapy in treatment of multiple bone metastases. ［Methods］ The fractionated treatment registration data of 15 patients in Tomotherapy with multiple bone metastases were collected，wherein the single-plan with multi-target 8 patients(group A) and multi-plan with single-target 7 patients(group B). Apply MVCT scan before each radiation therapy，automatic registration(Bone Technique) and manual registration were used to correct set-up errors. Then statistical software was used to compare the registration error of fractionated treatment in lateral(X-axis)，longitudinal(Y-axis)，vertical(Z-axis) and rotation(Roll).［Results］ Comparing Group A(8 patients，200 times online registration data)and Group B(7 patients，175 times online registration data)，the absolute error in Group A was higher than that in Group B only in longitudinal(Y-axis)(P=0.041)，they were (5.24±4.01)mm，(3.72±3.67)mm，respectively. The relative error in Group A was higher than that in Group B only in lateral(X-axis)(P=0.008)，they were(2.81±2.07)mm，(1.87±1.83)mm respectively.［Conclusions］ Two planning methods for registration accuracy of multiple bone metastasis fractionated treatment have advantages and disadvantages，and all in the range that can be controlled，so we can choose the appropriate plan based on clinical practice. |
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