| 徐月亮,王孝彬,韩 勇.早期非小细胞肺癌经电视胸腔镜和开胸手术治疗疗效的Meta分析[J].肿瘤学杂志,2016,22(7):583-588. |
| 早期非小细胞肺癌经电视胸腔镜和开胸手术治疗疗效的Meta分析 |
| Meta Analysis on the Efficacy of Video-assisted Thoracoscpic Surgery(VATS) and Thoracotomy Surgery for Non-small Cell Lung Cancer Early Stage |
| 投稿时间：2015-11-13 |
| DOI：10.11735/j.issn.1671-170X.2016.07.B012 |
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| 中文关键词: 电视胸腔镜手术 开胸手术 非小细胞肺癌 Meta分析 |
| 英文关键词:video-assisted thoracoscopic surgery thoracotomy non-small cell lung cancer Meta analysis |
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| 中文摘要: |
| 摘 要：［目的］ 评价电视胸腔镜手术（VATS）与开胸手术治疗早期非小细胞肺癌的近期疗效，以便为手术治疗决策提供依据。［方法］ 通过检索PubMed、Embase、The Cochrane Library、中国生物医学文献数据库(CBM)和中国期刊网全文数据库(CNKI)等数据库，收集VATS与开胸手术治疗早期非小细胞肺癌近期疗效的随机对照试验(RCT)，提取资料和评估方法学质量，采用Cochrane协作网RevMan5.3软件进行Meta分析。［结果］ 共有8篇文献纳入研究，共计1358例患者。Meta分析结果显示：与传统开胸手术治疗相比较，VATS可减少胸腔引流量，并降低术后总的并发症发生率，缩短术后住院时间；但手术时间、淋巴结清扫数目、术中出血量、术后胸管留置时间等相当。［结论］ 现有的临床资料显示：与开胸手术相比，VATS是治疗早期非小细胞肺癌更好的选择，可以作为早期非小细胞肺癌的常规治疗手段。 |
| 英文摘要: |
| Abstract：［Purpose］ To evaluate the efficacy of video-assisted thoracoscpic surgery(VATS) and thoracotomy surgery for non-small cell lung cancer(NSCLC) early stage，and to provide evidence for the treatment decision. ［Methods］ The randomized controlled trials(RCT) about the efficacy of VATS and thoracotomy surgery for early stage NSCLC were searched on PubMed，Embase，The Cochrane Library，Chinese Biomedical Literature Database(CBM) and China Journal Full-text Database (CNKI). By extracting data and assessing methodological quality，Meta analysis was conducted by the Cochrane Collaboration RevMan5.3 software. ［Results］ Eight articles and 1358 patients were included. Meta analysis indicated that，compared with the traditional thoracotomy surgery，VATS reduced chest drainage，and reduced overall postoperative complication rate，decreased postoperative hospital stay；and had the similar efficacy about the operation time，the number of lymph node dissection，blood loss，postoperative chest tube indwelling time. ［Conclusion］The limited clinical trials show there is some evidence supporting the use of VATS，and VATS might be a good alternative to traditional open lobectomy. |
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