| 于鹏丽,张 婕,闻宝杰.超声弹性应变率比值对BI-RADS 4级乳腺肿块良恶性诊断价值的分析[J].肿瘤学杂志,2016,22(6):439-442. |
| 超声弹性应变率比值对BI-RADS 4级乳腺肿块良恶性诊断价值的分析 |
| Ultrasonic Elastic Strain Rate Ratio in Differential Diagnosis of BI-RADS 4 Breast Lesions |
| 投稿时间：2016-02-16 |
| DOI：10.11735/j.issn.1671-170X.2016.06.B001 |
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| 中文关键词: 超声弹性成像 SR 乳腺肿块 BI-RADS |
| 英文关键词:ultrasonic elastography SR breast lesions BI-RADS |
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| 中文摘要: |
| 摘 要：［目的］ 探讨超声弹性成像应变率比值对BI-RADS 4级乳腺肿块良恶性的诊断价值。［方法］ 对182例（共208个肿块）BI-RADS 4级乳腺肿块行超声弹性成像检查，与病理对照，绘制ROC 曲线确定弹性应变率比值最佳鉴别诊断界值。并分析弹性应变率比值在BI-RADS 4A、4B、4C三类中的应用价值。［结果］ 弹性应变率比值最佳界值为0.495。弹性应变率比值在BI-RADS 4A类中差异无统计学意义，在BI-RADS 4B、4C类中差异具有统计学意义。弹性成像应变率比值鉴别诊断4B和4C类的灵敏度、特异性、准确性、阳性预测值分别为89.1%、77.3%、88.2%、92.0%和86.3%、80.1%、83.5%、93.3%。［结论］ 对于BI-RADS 4B、4C类，联合应用BI-RADS分级系统与弹性成像应变率比值具有较高的应用价值，提示恶性病灶可早期进行手术治疗；对于BI-RADS 4A类，弹性应变率应用价值有限。 |
| 英文摘要: |
| Abstract：［Objective］ To assess the diagnostic value of ultrasonic elastic strain rate ratio for BI-RADS 4 breast lesions.［Methods］ One hundred and eighty two patients with 208 BI-RADS 4 breast tumors(137 benign lesions and 71 malignant lesions)，underwent ultrasound elastography examination. With pathologic results as the reference standard，the receiver-operating characteristic curve(ROC) was used to identify the cut-off point for differential diagnosis of breast lesions. The application value of strain ratio in the BI-RADS 4A，4B and 4C three levels was analyzed. ［Results］ There were significant differences in ultrasonic elastic strain rate ratio between malignant and benign lesions in BI-RADS 4B and 4C breast tumors，but no difference in BI-RADS 4A tumors. Taking strain ratio of 0.495 as cut-off value，the sensitivity，specificity，accuracy and positive predictive value for differential diagnosis of malignant from benign tumors in groups BI-RADS 4B and 4C were 89.1%，77.3%，88.2%，92.0% and 86.3%，80.1%，83.5%，93.3% respectively. ［Conclusions］ The combination of BI-RADS classification and strain ratio may effectively differentiate the malignant nodules from the benign ones in BI-RADS 4B and 4C breast tumors；however，it is not applicable for BI-RADS 4A tumors. |
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