| 王倩青,岳爱民,李 君.25例宫颈癌保留自主神经功能手术对性功能影响的临床研究[J].肿瘤学杂志,2016,22(5):394-398. |
| 25例宫颈癌保留自主神经功能手术对性功能影响的临床研究 |
| Sexual Function in Cervical Cancer Patients Following Nerve-sparing Radical Hysterectomy |
| 投稿时间：2015-11-08 |
| DOI：10.11735/j.issn.1671-170X.2016.05.B012 |
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| 中文关键词: 自主神经 子宫切除术 盆腔淋巴结清扫术 性功能 |
| 英文关键词:autonomic nerve hysterectomy pelvic lymphadenectomy sexual function |
| 基金项目:河南省重点科技攻关计划项目(102102310101) |
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| 中文摘要: |
| 摘 要：［目的］ 探讨宫颈癌保留自主神经功能的子宫广泛切除及盆腔淋巴结清扫术对性功能的影响。［方法］ 49例宫颈癌患者随机分为保留自主神经功能的子宫广泛切除及盆腔淋巴结清扫术（NSRH术）组（25例，NSRH组）和传统子宫广泛切除及盆腔淋巴结清扫术（传统RH术）组（24例，RH组）。使用女性性功能量表(FsFx)对两组患者术前术后性功能状况进行评定。分析患者行保留自主神经功能的子宫广泛切除及盆腔淋巴结清扫术对性功能的影响。［结果］ 两组患者术前指标无显著差异，NSRH组术后腰腹痛、排便异常发生率低于RH组，差异有统计学意义（P＜0.05）。NSRH组患者术前术后性欲望、性唤起及高潮、阴道润滑及性交痛、性满意度4项比较无显著性差异，总体性功能评分术前（80.62±18.21）、术后（75.22±17.96）差异无统计学意义（P>0.05）。而RH组患者术后（62.13±15.54）总体性功能评分明显低于术前（79.40±16.26），差异具有统计学意义（P<0.05）。组间比较：术后两组患者性欲望和性满意度比较无显著性差异（P>0.05）；但在性唤起及高潮、阴道润滑及性交痛、总体性功能评分上RH组显著低于NSRH组（P<0.05）。［结论］ 保留自主神经功能的子宫广泛切除及盆腔淋巴结清扫术对女性性欲望及满意度上无明显影响，但对性唤起及高潮、阴道润滑及性交痛等性生活质量上有明显改善，值得在临床上推广。 |
| 英文摘要: |
| Abstract：［Objective］ To assess the sexual function in cervical cancer patients following nerve-sparing radical hysterectomy(NSRH). ［Methods］ Forty-nine patients with cervical cancer were randomly divided into two groups：25 cases received NSRH with pelvic lymphadenectomy(NSRH group) and 24 cases received conventional radical hysterectomy with pelvic lymphadenectomy (RH group). The sexual functions of patients were assessed with Female Sexual Function Index (FsFx) before and after surgical treatment in two groups. ［Results］ There was no significant difference in preoperative indicators between two groups. The incidence of abdominal pain and abnormal defecation in NSRH group was significantly lower than that in RH group(P<0.05). There were no significant differences in sexual desire，sexual arousal and orgasm，vaginal lubrication and dyspareunia，sexual satisfaction in NSRH group before and after surgery；and there was no significant difference in preoperative sexual function score(80.62±18.21) and postoperative score(75.22±17.96)(P>0.05). While in RH group，the postoperative sexual function score(62.13±15.54) was significant lower than that in preoperative patients(79.40±16.26)(P<0.05). There was no significant difference in postoperative sexual desire and satisfaction between two groups(P>0.05). But the postoperative scores of sexual arousal and orgasm，vaginal lubrication and dyspareunia，as well as the overall sexual function score in RH group were significantly lower than those in NSRH group (P<0.05). ［Conclusion］ Compared to conventional radical hysterectomy，the nerve-sparing radical hysterectomy with pelvic lymphadenectomy may result in better postoperative quality of sexual life for cervical cancer patients. |
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