王丽娜,徐春华,于力克.贫血对91例晚期非小细胞肺癌患者预后的影响[J].肿瘤学杂志,2016,22(3):180-183.
贫血对91例晚期非小细胞肺癌患者预后的影响
The Effect of Anemia on the Prognosis of 91 Cases with Advanced Non-small Cell Lung Cancer
投稿时间:2015-11-10  
DOI:10.11735/j.issn.1671-170X.2016.03.B005
中文关键词:  贫血  非小细胞肺癌  预后
英文关键词:anemia  non-small cell lung cancer(NSCLC)  prognosis
基金项目:
作者单位
王丽娜 芜湖海螺医院 
徐春华 南京市胸科医院 
于力克 南京市胸科医院 
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中文摘要:
      摘 要:[目的] 探讨贫血对晚期非小细胞肺癌(NSCLC)患者预后的影响。[方法] 回顾性分析91例晚期NSCLC患者初诊时血红蛋白(HGB)水平,比较贫血组和非贫血组生存期的差异,分析NSCLC患者的预后影响因素。[结果] 非贫血组的中位生存期较贫血组长,有统计学差异(14.7个月 vs 10.4个月,P<0.05)。经Cox多因素分析发现,贫血、临床分期Ⅳ期是预后不良的独立危险因素。[结论] 贫血缩短NSCLC患者的生存期,是影响预后的独立因素。
英文摘要:
      Abstract:[Purpose] To investigate the effect of anemia on the prognosis of advanced non-small cell lung cancer(NSCLC) patients. [Methods] Hemoglobin(HGB) level of 91 cases with NSCLC initially diagnosed was analyzed retrospectively. The difference of survival between anemia group and non-anemia group was compared,the factors influencing prognosis of NSCLC were analyzed. [Results] The median survival time in non-anemia group was longer than that in anemia group,with significant difference between them(14.7months vs 10.4months,P<0.05).Cox multivariate analysis showed that anemia and clinical stage Ⅳ were independent risk factors for poor prognosis. [Conclusion] Anemia shorten survival of NSCLC patients,and it is an independent prognostic factor for NSCLC patients.
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