| 邵 琦,陈丽羽,周玲燕.颈部转移性淋巴结超声造影时间—强度曲线分析[J].肿瘤学杂志,2016,22(1):33-38. |
| 颈部转移性淋巴结超声造影时间—强度曲线分析 |
| Time-intensity Curve Analysis of Contrast-enhanced Ultrasound for Metastatic Cervical Lymph Nodes |
| 投稿时间：2015-08-05 |
| DOI：10.11735/j.issn.1671-170X.2016.01.B007 |
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| 中文关键词: 淋巴结 超声造影 时间—强度曲线 鉴别诊断 |
| 英文关键词:lymph nodes contrast-enhanced ultrasound (CEUS) time-intensity curve (TIC) differential diagnosis |
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| 中文摘要: |
| 摘 要：［目的］ 分析颈部转移性淋巴结超声造影时间—强度曲线特点，以探讨超声造影对诊断颈部转移性淋巴结的价值。［方法］ 对75例颈部淋巴结病变的患者进行超声造影检查，共75枚淋巴结（反应性增生34枚，转移性41枚）。整个淋巴结设为感兴趣区，如有坏死液化及范围较大的钙化区，则剔除此无血供区。对获得的时间—强度曲线参数（基础强度、峰值强度、上升支斜率、始增时间、达峰时间、上升时间、峰值浓度减半时间、平均渡越时间）进行比较分析。［结果］ 峰值强度：转移性淋巴结（51.8181±6.2808）dB，反应性增生淋巴结（58.0895±5.7174）dB，P<0.01；上升支斜率：转移性淋巴结1.8266±0.6738，反应性增生淋巴结0.9451±0.6639，P<0.01；上升时间：转移性淋巴结（5.5057±1.2348）s，反应性增生淋巴结（6.3841±2.1820）s，P=0.032。转移性淋巴结峰值强度低于反应性增生淋巴结，上升时间短于后者，上升支斜率小于后者，差异均有统计学意义（P<0.05），而二者间的始增时间、达峰时间、峰值浓度减半时间及平均渡越时间等的差异无统计学意义。［结论］ 转移性淋巴结与反应性增生淋巴结在超声造影时间—强度曲线中的差异可为鉴别诊断提供更多参考信息，对临床诊断具有指导意义。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigte the feature of the time-intensity curve(TIC) of contrast-enhanced ultrasound (CEUS) on metastatic cervical lymph nodes，and to investigate the application value of CEUS to the differential diagnosis of metastatic cervical lymph nodes. ［Methods］ Seventy-five cases with cervical lymph node lesions were examined with CEUS. Of 75 lymph nodes，34 benign and 41 malignant lesions were proved by histopathology. Region of interest(ROI) was placed in whole lymph nodes. Eight TIC parameters (basic intensity，peak intensity，ascending slope，arrival time，time to peak，rise time，time from peak to one half，and mean transit time) were compared and analyzed between benign and malignant lymph nodes. ［Results］ The peak intensity of the metastatic cervical lymph nodes was (51.8181±6.2808)dB，and the one of benign cervical lymph nodes was(58.0895±5.7174)dB(P<0.01)； The ascending slope of the metastatic cervical lymph nodes was 1.8266±0.6738，and the one of benign cervical lymph nodes was 0.9451±0.6639(P<0.01)； The rise time of the metastatic cervical lymph nodes was (5.5057±1.2348)s，and the one of benign cervical lymph nodes was (6.3841±2.1820)s (P=0.032). The peak intensity，ascending slope and rise time were significantly different between metastatic and benign cervical lymph nodes. There were no significant differences in other TIC parameters between metastatic and benign cervical lymph nodes. ［Conclusion］ The differences in TIC of CEUS between metastatic and benign cervical lymph nodes offer great values for the differential diagnosis. |
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