| 杨 晗,马毓梅,夏 娜.49例晚期高级别浆液性卵巢癌的预后相关因素分析[J].肿瘤学杂志,2015,21(11):880-884. |
| 49例晚期高级别浆液性卵巢癌的预后相关因素分析 |
| An Analysis on Prognostic Factors in 49 Cases with Advanced High Grade Serous Ovarian Cancer |
| 投稿时间：2015-07-07 |
| DOI：10.11735/j.issn.1671-170X.2015.11.B004 |
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| 中文关键词: 浆液性肿瘤 卵巢肿瘤 预后 肿瘤细胞减灭术 |
| 英文关键词:serous neolasms ovarian neoplasms prognosis tumor cytoreductive surgery |
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| 中文摘要: |
| 摘 要：［目的］ 探讨影响晚期（Ⅲ期和Ⅳ期）高级别浆液性卵巢癌预后的相关因素。［方法］ 回顾性分析49例晚期高级别浆液性卵巢癌的预后相关因素。［结果］ 49例晚期高级别浆液性卵巢癌的5年生存率为33.00%，中位生存时间为47.06个月。单因素分析显示年龄、FIGO分期、术后残留灶、阑尾转移、淋巴结转移、化疗周期是影响晚期高级别浆液性卵巢癌患者预后的重要因素。多因素分析显示年龄、FIGO分期和术后化疗周期是影响其预后的独立危险因素。［结论］ 晚期高级别浆液性卵巢癌在初始肿瘤细胞减灭术后，配合以铂类为基础的化疗，有助于改善患者的预后。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the prognostic factors of advanced (stage Ⅲ and Ⅳ) high grade serous ovarian cancer. ［Methods］ Prognosis related factors such as age，FIGO stage，residual tumor after surgery，appendix and lymph node status，cycle of chemotherapy were analyzed retrospectively in 49 cases with advanced high grade serous ovarian cancer. ［Result］ The 5-year survival rate was 33.00% and the median survival time was 47.06 months. Univariate analysis revealed that age，FIGO stage，residual tumor after surgery，appendix metastasis and lymph node metastasis，cycle of chemotherapy were important prognostic factors. Multivariate analysis revealed that age，FIGO stage and cycle of chemotherapy were independent prognostic factors of 49 cases with advanced high grade serous ovarian cancer. ［Conclusion］ The optimal tumor cytoreductive surgery and postoperative chemotherapy based on platinum might significantly improve the prognosis of patients with advanced high grade serous ovarian cancer. |
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