| 邓文英,许勇飞,李 宁.20例胃小细胞癌的临床分析[J].肿瘤学杂志,2015,21(9):734-736. |
| 20例胃小细胞癌的临床分析 |
| Clinical Analysis on 20 cases with Gastric Small Cell Carcinoma |
| 投稿时间：2014-05-08 |
| DOI：10.11735/j.issn.1671-170X.2015.09.B007 |
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| 中文关键词: 胃肿瘤 小细胞癌 治疗 预后 |
| 英文关键词:gastric neoplasms small cell carcinoma treatment prognosis |
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| 中文摘要: |
| 摘 要：［目的］ 探讨胃小细胞癌的临床特点、临床诊断、治疗方法及预后。［方法］回顾性分析20例胃小细胞癌患者的临床资料。［结果］ 20例患者中， 17例行手术治疗，其中13例行根治性肿瘤切除术，4例行姑息性手术；3例行单纯化疗。全组患者中位生存时间为11个月，1、2、3年生存率分别为60.1％、26.2％和12.7％。患者的预后与肿瘤分期、有无淋巴结转移和手术根治程度有关（P<0.05），而与年龄、性别无关(P>0.05)。［结论］ 胃小细胞癌是胃恶性肿瘤中的罕见病理类型，恶性程度高，病情进展迅速,治疗方法以手术、化疗、放疗为主，总体疗效不佳。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the clinical characteristics，diagnosis，treatment and prognosis of gastric small cell carcinoma. ［Methods］ Clinical data of 20 cases with gastric small cell carcinoma were analyzed retrospectively．［Results］ Of 20 cases，17 cases underwent surgical treatment，including radical resection in 13 cases，palliative surgery in 4 cases，and chemotherapy alone in 3 cases. The overall median survival was 11 months，and 1-，2-，and 3-year survival rates were 60.1%，26.2% and 12.7% respectively. The prognosis of patients related to tumor staging，lymph node metastasis and radical grade of the operation(P<0.05)，but not related to age and gender(P>0.05). ［Conclusion］ Gastric small cell carcinoma is a rare pathological type of gastric malignant tumor，with high aggression and rapid disease progression. Surgery，chemotherapy and radiotherapy are the common treatment methods，and the prognosis of the disease is poor. |
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