| 中文关键词: 胰腺肿瘤 肿瘤干细胞 信号通路 靶向治疗 |
| 英文关键词:pancreas neoplasms cancer stem cells signaling pathway target therapy |
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| 摘要点击次数: 1923 |
| 全文下载次数: 1214 |
| 中文摘要: |
| 摘 要：胰腺癌干细胞在胰腺癌的发生发展过程中起着很关键的作用。最近不断有报道证实针对肿瘤干细胞的治疗可以明显减弱肿瘤干细胞的信号传导。因此胰腺癌干细胞靶向治疗药物可以明显改善胰腺癌患者的预后。现对胰腺癌干细胞靶向治疗的进展作一综述。 |
| 英文摘要: |
| Abstract：Emerging evidence suggests that pancreatic cancer stem cells (CSCs) play a crucial role in the development and progression of pancreatic cancer. Recently，there is increasing evidence showing that treatment targeted CSCs could attenuate cell signaling conduction in CSCs. Therefore，agents targeted pancreatic cancer CSCs might improve the prognosis of pancreatic cancer. Advances of target therapy for pancreatic cancer CSCs are reviewed in this article. |
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