| 李 晴,汪艳珠,黄卓敏.宫颈高级别CIN术后残留临床结局研究[J].肿瘤学杂志,2015,21(5):415-418. |
| 宫颈高级别CIN术后残留临床结局研究 |
| Clinical Outcome of Postoperative Residue of Cervical High Grade CIN |
| 投稿时间：2015-01-19 |
| DOI：10.11735/j.issn.1671-170X.2015.05.B014 |
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| 中文关键词: 宫颈上皮内瘤变 残留 复发 环状电极切除术（LEEP） 冷刀锥切术（CKC） |
| 英文关键词:cervical intraepithelial neoplasia(CIN) residue recurrence loop electrosurgical excision procedure(LEEP) cold knife conization(CKC) |
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| 中文摘要: |
| 摘 要：［目的］ 总结宫颈高级别CIN术后残留、复发特点，探讨CIN病例术后临床复诊的重要性。［方法］ 宫颈高级别CIN行锥切手术治疗595例，术后病理诊断残留58例，术后第4个月开始定期随访，随访手段为HPV检测、阴道镜检查、细胞学检查，必要时进行活检及ECC。［结果］ 595例手术后病灶残留58例，残留阳性率9.75%，其中CIN2残留阳性率1.46%，实际残留率0，HPV持续阳性率0；CIN3残留阳性率14.10%，实际残留率2.05%，HPV持续阳性率1.03%。［结论］ 高级别CIN术后病理诊断边缘或/和基底有病灶残留，需要在随访中进一步明确，对实际残留病例应把握处理时机及恰当的处理方法。 |
| 英文摘要: |
| Abstract：［Purpose］ To summarize the characteristics of postoperative residue and relapse of cervical high grade CIN and to investigate the importance of clinical follow-up of CIN postoperative patients. ［Methods］ Five hundred and ninety-five high grade CIN patients underwent conization. Among them，58 patients were diagnosed as residual cases and were regularly followed up. Follow-up methods included HPV DNA genotyping，colposcope，cytologic examination，and performing biopsy and ECC when necessary. ［Results］ The overall residual positive rate of 595 postoperative patients was 9.75%(58 cases). The residual positive rate of CIN2，the actual residual rate and the continual positive rate of HPV were 1.46%，0 and 0，respectively. The residual positive rate of CIN3，the actual residual rate and the continual positive rate of HPV were 14.10%，2.05% and 1.03%，respectively. ［Conclusion］ Postoperative follow-up should perform on high grade CIN patients if residual lesion is diagnosed in margin and/or base tissue after opertation. Postoperative actual residual patients should be dealed with at an appropriate time and in a proper method. |
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