| 张周芳,黄洁惠,邵国良.双源CT双能量成像在肺癌病理类型鉴别中的应用价值[J].肿瘤学杂志,2015,21(5):392-395. |
| 双源CT双能量成像在肺癌病理类型鉴别中的应用价值 |
| Application Value of Dual-energy CT Imaging in the Differential Diagnosis of Pathological Types of Lung Cancer |
| 投稿时间：2015-01-15 |
| DOI：10.11735/j.issn.1671-170X.2015.05.B009 |
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| 中文关键词: 双源CT 双能量 肺肿瘤 鉴别诊断 |
| 英文关键词:dual-source CT dual-energy lung neoplasms |
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| 中文摘要: |
| 摘 要：［目的］探讨双源CT双能量成像在肺鳞癌及腺癌病理类型鉴别中的临床应用价值。［方法］ 收集初诊肺癌患者，鳞癌14例，腺癌21例，均使用双源CT双能量模式行多期（主动脉达峰时、第40s、第60s、第100s）增强扫描，在后处理工作站MMWP上得到纯碘图图像，再通过Volume软件计算出CT净增值，分析腺癌与鳞癌各期净增值的差异及其时间—密度曲线特征。［结果］ 各期扫描中，腺癌CT净增值均大于鳞癌，其中在主动脉达峰时及第100s，两组间差异有统计学意义（P<0.05），而第40s及第60s，两组间差异无统计学意义（P>0.05）。腺癌与鳞癌时间—密度曲线表现不同，腺癌CT净增值随时间变化而增大，鳞癌第40s达到高峰，随后下降。［结论］ 双源CT双能量成像多期增强扫描可为影像学鉴别诊断腺癌与鳞癌提供一定的依据。 |
| 英文摘要: |
| Abstract：［Purpose］To investigate the clinical application value of dual energy CT imaging in the differential diagnosis of pulmonary squamous cell carcinoma and adenocarcinoma.［Methods］ Thirty-five initially diagnosed lung cancer patients including 14 cases with squamous cell carcinoma，21 cases with adenocarcinoma，underwent enhanced dual-source CT scaning in dual-energy pattern in the period of aortic peak，40s，60s and 100s.The pure iodine images were obtained from MMWP workstation and the net enhancement CT value was calculated through the Volume software.The differences of the net enhancement CT value in each period and the characteristics of time-density cures between adenocarcinoma and squamous cell carcinoma were analyzed.［Results］ The net enhancement CT value of adenocarcinoma was greater than that of squamous cell carcinoma in each phase，and statistical significance was found between the two groups at both the aortic peak and 100s（P<0.05），but no difference was found at both the 40s and 60s（P>0.05）. The characteristics of time-density curve between the two groups was different.The net enhancement CT value of adenocarcinoma increased with time going；And in squamous cell carcinoma ，the net enhancement CT value increased to the peak at 40s ，then decreased. ［Conclusion］ Multiple phase enhanced scanning of dual-energy CT imaging might provide a basis for diagnosis of adenocarcinoma and squamous cell carcinoma of the lung. |
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