| 尹飞飞,孙世波,杨艳梅.趋化因子及受体在肝癌侵袭转移中的研究进展[J].肿瘤学杂志,2015,21(3):242-245. |
| 趋化因子及受体在肝癌侵袭转移中的研究进展 |
| Research Progress of Chemokines and Chemokine Receptors in Invasion and Metastasis of Hepatocellular Carcinoma |
| 投稿时间：2014-01-01 |
| DOI：10.11735/j.issn.1671-170X.2015.03.B016 |
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| 中文关键词: 趋化因子 受体，趋化因子 肝细胞癌 侵袭 肿瘤转移 |
| 英文关键词:chemokine receptor,chemokine hepatocellular carcinoma invasion |
| 基金项目: |
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| 摘要点击次数: 1903 |
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| 中文摘要: |
| 摘 要：近年来趋化因子及其受体领域已经受到广泛关注。它们是一个促炎多肽细胞因子的超家族，具有众多成员。趋化因子及其相应的受体在多种生理和病理过程中发挥着重要作用。研究表明，它们与肿瘤的血管生成、发生发展、侵袭转移及治疗预后都有着密切关系。文章就趋化因子及其受体在肝癌侵袭转移中的机制及其研究进展作一综述。 |
| 英文摘要: |
| Abstract：In recent years，the field of chemokines and their receptors has aroused wide concern. They belong to a super family of proinflammatory peptides cytokine with many members. Chemokines and their corresponding receptors play an important role in a variety of physiological and pathological process. Studies have shown that they have a close relationship with angiogenesis，development，invasion，metastasis，treatment and prognosis of the tumor. In this paper，mechanism and research progress of chemokines and their receptors in invasion and metastasis of hepatocellular carcinoma are reviewed. |
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