| 王利欢,李月敏,张玉海.晚期胸腺癌19例临床病理与预后分析[J].肿瘤学杂志,2015,21(3):228-232. |
| 晚期胸腺癌19例临床病理与预后分析 |
| Clinicopathological Features and Prognosis of 19 Cases with Advanced Thymic Carcinoma |
| 投稿时间：2014-10-25 |
| DOI：10.11735/j.issn.1671-170X.2015.03.B013 |
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| 中文关键词: 胸腺肿瘤 临床病理学 综合治疗 预后 外科手术 |
| 英文关键词:thymic neoplasms clinicopathology comprehensive treatment prognosis surgery |
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| 中文摘要: |
| 摘 要：［目的］探讨晚期胸腺癌的临床病理特点及预后。［方法］回顾性分析19例经病理或细胞学检查证实的晚期胸腺癌患者的临床病理资料。［结果］鳞癌占全部患者的 63.2%。全组患者3 年生存率为 46.7%。手术患者与非手术患者的 3 年生存率分别为 83.3% 和 22.2% （P<0.05）。完整切除与未完整切除（包括部分切除和手术探查） 的患者3 年生存率分别为 100.0% 和 60.0%（P>0.05）。放疗患者与非放疗患者的 3 年生存率分别为 50.0% 和 33.3%（P>0.05）。 Ⅲ期与Ⅳ期患者的 3 年生存率分别为 71.4% 和 25.0% （P>0.05）。高分化癌（鳞癌）和低分化癌（神经内分泌癌、未分化癌）的 3 年生存率分别是 50.0% 和 42.9% （P>0.05）。［结论］鳞癌是最常见的胸腺癌病理亚型。晚期胸腺癌患者应尽可能完整手术切除，术后辅以放化疗。手术切除、WHO 病理分型影响胸腺癌患者预后。 |
| 英文摘要: |
| Abstract：［Purpose］To investigate the clinicopathological features and prognosis of advanced thymic carcinoma.［Methods］The data from 19 patients with advanced thymic carcinoma pathologically or cytologically confirmed were analyzed retrospectively.［Results］Squamous cell carcinoma accounted for 63.2% of the total cases. The overall 3-year survival rate was 46.7%. 3-year survival rate for patients with surgical resection and without resection was 83.3% and 22.2%（P<0.05）respectively. 3-year survival rate for complete resection and non-complete resection patients was 100.0% and 60.0%（P>0.05）respectively. 3-year survival rate for patients with radiotherapy and without radiotherapy was 50.0% and 33.3%（P>0.05）respectively. 3-year survival rate for stage Ⅲ and stage Ⅳpatients was 83.3% and 22.2%（P>0.05）respectively. 3-year survival rate for low and high grade groups was 50.0% and 42.9%（P>0.05）respectively.［Conclusion］The most common histological subtype is squamous cell carcinoma. The main treatment modality for advanced thymic carcinoma is complete resection，followed by chemoradiotherapy. Surgery and WHO pathologic typing influence the prognosis of thymic carcinoma patients. |
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