| 彭 涛,杨永江,赵轶峰.108例Tis~1N0M0期中低位直肠癌经肛门局部切除的临床评价[J].肿瘤学杂志,2015,21(2):106-108. |
| 108例Tis~1N0M0期中低位直肠癌经肛门局部切除的临床评价 |
| Clinical Evaluation of Transanal Local Excision in 108 Cases with Tis~1N0M0 Middle and Low Rectal Carcinoma |
| 投稿时间：2014-05-30 |
| DOI：10.11735/j.issn.1671-170X.2015.02.B007 |
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| 中文关键词: 直肠肿瘤 局部治疗 经肛门切除 |
| 英文关键词:rectal neoplasms local therapy transanal excision |
| 基金项目: |
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| 中文摘要: |
| 摘 要：［目的］ 探讨Tis~1N0M0期中低位直肠癌经肛门局部切除的合理性。［方法］ 回顾性分析经肛门局部切除治疗的108例Tis~1N0M0期中低位直肠癌患者的资料。其中TisN0M0 63例，T1N0M0 45例。8例T1期患者接受了术后辅助放疗。［结果］ 所有患者术后恢复顺利，中位住院时间5d（3～8d）。无吻合口漏、直肠狭窄、肛瘘及其他手术并发症。术后肛门括约肌功能良好。5年总生存率为99.07%，Tis、T1期5年生存率分别为100%和97.78%。5年总复发率为1.85%，Tis、T1期5年复发率分别为0、4.44%。［结论］ 对Tis~1N0M0期中低位直肠癌患者，经肛门局部切除术既保证了生存率，又兼顾了患者的生存质量，为一种较为理想的术式选择。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the retionality of transanal excision for the Tis~1N0M0 rectal cancer. ［Methods］ One hundred and eight cases with stage Tis~1N0M0 rectal cancer underwent transanal local excision(Tis：63 cases；T1：45 cases). Eight cases stage T1 received post-operative radiation therapy. ［Results］ There was no perioperative death. Fecal continence was good postoperation. There was no anastomotic leak，proctostenosis and anal fistula. The overall 5-year survival rate was 99.07%. The 5-year survival rate was 100% in patients stage Tis and 97.78% in patients stage T1. The overall 5-year recurrence rate was 1.85%. Local tumor recurrence rate was 0 in patients stage Tis and 4.44% in patients stage T1. ［Conclusion］ Transanal local excision for Tis~1N0M0 middle or low rectal cancer results in a low complication rate and good sphincter function，and provides satisfactory local control and 5-year survival rates. This approach could be safely applied to Tis~1N0M0 rectal cancer. |
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