| 李 晨,吴玉梅.卵巢癌与相关分子转移机制的研究进展[J].肿瘤学杂志,2015,21(1):61-65. |
| 卵巢癌与相关分子转移机制的研究进展 |
| Research Progress on Ovarian Cancer and Its Related Molecular Metastatic Mechanism |
| 投稿时间：2013-11-21 |
| DOI：10.11735/j.issn.1671-170X.2015.01.B014 |
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| 中文关键词: 卵巢肿瘤 腹腔转移 肿瘤转移 分子机制 |
| 英文关键词:ovarian neoplasms neoplasm metastasis molecular mechanism |
| 基金项目: |
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| 中文摘要: |
| 摘 要：卵巢癌是死亡率最高的妇科肿瘤。由于早期症状不明显，多数患者发现时已是晚期，而晚期患者缺乏有效的治疗方案，其5年生存率不到40%。约70%卵巢癌患者伴有广泛的腹膜转移，一旦发生了转移，卵巢癌患者的预后将大大下降。所以卵巢癌转移的发病机制研究成为亟待解决的问题，该文就目前国内外关于卵巢癌转移的研究进展作一综述。 |
| 英文摘要: |
| Abstract：Ovarian cancer has the highest mortality among gynecologic cancer. Ovarian cancer’s lethality primarily stems from the inability to detect the disease at an early，organ-confined stage，and the lack of effective therapies for advanced disease. Indeed，despite treatment improvements，the majority of women continue to present at advanced stages with a 5-year survival rate of less than 40%. Most of patients have developed to the late stage when diagnosed. Approximately 70% of patients with advanced stage ovarian cancer have widespread metastases，including the formation of malignant serous effusion. When metastasis occurs，ovarian cancer is currently incurable. So there is a need for a better understanding of the mechanisms of metastasis of ovarian cancer. This article mainly reviews on the research progress on the metastasis of ovarian cancer. |
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