许亚萍,毛伟敏.食管鳞状细胞癌术后辅助治疗研究进展[J].肿瘤学杂志,2015,21(1):56-60. |
食管鳞状细胞癌术后辅助治疗研究进展 |
The Current Status of Adjuvant Therapy for Esophageal Squamous Cell Carcinoma Postoperation |
投稿时间:2014-11-25 |
DOI:10.11735/j.issn.1671-170X.2015.01.B013 |
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中文关键词: 食管肿瘤 鳞状细胞癌 外科手术 辅助治疗 |
英文关键词:esophageal neoplasms squamous cell carcinoma surgery adjuvant therapy |
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中文摘要: |
摘 要:手术是可切除食管癌的主要治疗手段,但单纯手术疗效较差。CROSS研究的发表使新辅助放化疗成为食管癌研究的热点,并成为以腺癌为主的西方国家的标准治疗手段。而我国,90% 以上的患者为鳞状细胞癌。近年来,术后辅助治疗在食管鳞状细胞癌中也进行了较为深入的研究。文章主要就食管鳞状细胞癌术后辅助治疗的研究进展进行综述。 |
英文摘要: |
Abstract:Surgery is the preferred therapeutic strategy for esophageal cancer. But,most of patients still die of recurrence or distant metastases even in the presence of radical resection and extended lymph node dissection. Since the Chemoradiation therapy for Oesophageal cancer followed by Surgery Study (CROSS),preoperative chemoradiation therapy is considered the standard of care in Western countries where most of esophageal cancer cases are adenocarcinoma. However,more than 90% of esophageal cancer is pathologically diagnosed as squamous cell carcinoma in China. For several decades,there have been numerous efforts on adjuvant therapy to improve poor outcomes of locally advanced esophageal squamous cell carcinoma. In this article,the current status of adjuvant therapy in esophageal squamous cell carcinoma postoperation are reviewed. |
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