李小平,郑磊贞.胰腺癌干细胞表面标志物的研究进展[J].肿瘤学杂志,2014,20(12):1040-1045. |
胰腺癌干细胞表面标志物的研究进展 |
Research Progress in Stem Cell Markers of Pancreatic Cancer |
投稿时间:2014-02-17 |
DOI:10.11735/j.issn.1671-170X.2014.12.B015 |
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中文关键词: 胰腺肿瘤 干细胞 标志物 |
英文关键词:pancreatic neoplasms stem cell marker |
基金项目: |
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摘要点击次数: 2019 |
全文下载次数: 885 |
中文摘要: |
摘 要:胰腺癌预后极差。近年来,肿瘤干细胞理论引起人们的关注。对胰腺癌干细胞自我更新和耐药机制的深入研究可能会发现对胰腺癌更有效的治疗措施。目前许多实体瘤肿瘤干细胞的分离鉴定还相当困难,主要是因为缺乏特异的肿瘤干细胞分子标志。现对胰腺癌干细胞表面标志物的研究现状作一综述。 |
英文摘要: |
Abstract:The survival rates of pancreatic cancer have seen minimal improvement over the past few decades. Biomarkers play a promising role in the development of personalized treatments for patients with pancreatic cancer. Prognostic biomarkers,such as cancer stem cell markers,provide valuable insight into the biological processes of disease. As research progresses,more evidence will provide clinicians with guidelines on the utilization of biomarkers to accurately stage and tailor personalized treatment to the needs of pancreatic cancer patients. This review aims to explore the pancreatic cancer stem cell markers. |
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