| 邢彦粉,李 振,魏生峰.肺不典型腺瘤样增生与原位腺癌的多层螺旋CT征象对照分析[J].肿瘤学杂志,2014,20(11):936-941. |
| 肺不典型腺瘤样增生与原位腺癌的多层螺旋CT征象对照分析 |
| Comparison Analysis of MSCT Between Atypical Adenomatous Hyperplasia and Adenocarcinoma in Situ of Lung |
| 投稿时间：2014-07-11 |
| DOI：10.11735/j.issn.1671-170X.2014.11.B013 |
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| 中文关键词: 硬币病变 肺 体层摄影术，X线计算机 |
| 英文关键词:coin lesion pulmonary tomography,X-ray computed |
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| 中文摘要: |
| 摘 要：［目的］ 对不典型腺瘤样增生（AAH）与原位腺癌（AIS）的多层螺旋CT（MSCT）征象进行对照分析，以提高AAH 和AIS 的诊断水平。［方法］ 回顾性分析经病理证实的59例AAH和35例AIS的MSCT征象（病灶分布、大小、形状、边缘形态、内部结构及邻近结构改变），用卡方检验或Fisher确切概率法进行统计学分析。 ［结果］ AAH 和AIS 的分布部位、范围、形状和瘤—肺界面差异均无统计学意义（χ2=4.092、1.283、0.000、0.170，P均>0.05）。纯磨玻璃结节（pGGN）和混合性磨玻璃结节（mGGN）的浅分叶征、细小毛刺征、空泡征差异有统计学意义（χ2=17.399、20.490、8.866和5.641、4.804、5.546，P均<0.05）；组间支气管充气征、胸膜凹陷征、穿行血管形态改变差异无统计学意义（χ2=2.984、3.445、2.836和0.781、1.128、1.172，P均>0.05）。pGGN 组AAH 和AIS 的大小差异无统计学意义（χ2=1.964，P>0.05），该组AAH 和AIS 的浅分叶征、细小毛刺征、胸膜凹陷征和穿行血管形态改变差异均有统计学意义（χ2=12.543、4.519、5.455、24.614，P均<0.05）；mGGN 组AAH 和AIS 的大小差异有统计学意义（χ2=7.201，P<0.05），该组AAH 和AIS的浅分叶征、细小毛刺征、空泡征、支气管充气征、胸膜凹陷征差异均无统计学意义（χ2=3.061、2.667、2.030、0.672、0.875，P均>0.05），穿行血管形态学改变在AAH和AIS组间差异有统计学意义（χ2=12.255，P<0.05）。［结论］ 通过对AAH 和AIS 的MSCT 征象对照分析，发现AAH和AIS 的影像学征象差异具有一定的统计学意义，有助于两者的鉴别诊断。 |
| 英文摘要: |
| Abstract：［Purpose］ To improve the diagnosis of atypical adenomatous hyperplasia(AAH) and adenocarcinoma in situ (AIS) by comparison analysis of imaging findings on MSCT of the two diseases. ［Methods］ We evaluated 59 cases of AAH and 35 cases of AIS confirmed by histopathology. Comparison of MSCT features as size，shape，margin，internal characteristics and adjacent structure of lesions were respectively analyzed. ［Results］ No differences were found in location，distribution，shape and well-defined between AAH and AIS（χ2=4.092，1.283，0.000， 0.170；P>0.05). There were significant differences in lobulated，speculated and vacuole sign between pGGN and mGGN(χ2=17.399，20.490，8.866 and 5.641，4.804，5.546；P<0.05)，while no difference was found in air bronchogram，pleural indentation sign and vascular morphological changes in the two groups(χ2=2.984，3.445，2.836 and 0.781，1.128，1.172；P>0.05).In the group of pGGN the size of AAH and AIS was found no difference (χ2=1.964，P>0.05)，while significant differences were found in lobulated，spiculation，pleural indentation sign and vascular morphological changes between AAH and AIS (χ2=12.543，4.519，5.455，24.614；P<0.05). In the group of mGGN the size of AAH and AIS was found significant difference(χ2=7.201，P<0.05)，while no differences were found in lobulated，spiculation，vacuole sign，air-bronchogram and pleural indentation sign(χ2=3.061，2.667，2.030，0.672，0.875；P>0.05)，only vascular morphological changes was found significant difference between AAH and AIS(χ2=12.255，P<0.05).［Conclusion］ The comparison analysis of AAH and AIS on MSCT findings shows that there are some significance differences between the two diseases，which can be helpful for the differential diagnosis. |
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