| 陈 珏,肖建军.114例小肝癌预后因素分析[J].肿瘤学杂志,2014,20(9):746-750. |
| 114例小肝癌预后因素分析 |
| An Analysis on Prognostic Factors for 114 Cases with Small Liver Cancer |
| 投稿时间：2014-03-19 |
| DOI：10.11735/j.issn.1671-170X.2014.09.B012 |
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| 中文关键词: 肝肿瘤 预后 门脉癌栓 临床病理学 |
| 英文关键词:liver neoplasms prognosis portal vein tumor thrombus clinicopathology |
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| 中文摘要: |
| 摘 要：［目的］分析小肝癌的临床、病理特点和预后因素。［方法］ 回顾性分析114例小肝癌患者的临床病理资料，对各临床病理因素与预后的关系进行分析。［结果］ 患者1、3、5年生存率分别为85.09%、69.30%、56.14%。单因素分析显示肿瘤大小、血清AFP水平等是预后影响因素，多因素分析则显示肿瘤大小、肝功能Child分级、肝硬化及门静脉癌栓是独立预后因素（RR=3.07，4.43，7.05，14.02，P均＜0.01）。［结论］ 小肝癌具有与大肝癌相同的肝病史，门脉癌栓是最有价值的预后指标，早期发现及手术切除，能有效提高生存率。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the clinicopathologic features and prognostic factors of small liver cancer. ［Methods］ One hundred and fourteen cases with small liver cancer were enrolled. The relationship between various clinicopathologic factors and prognosis of the patients with small liver cancer was analyzed. ［Results］ The 1-，3- and 5-year survival rates of the patients were 85.09%，69.30% and 56.14% respectively. Univariate analysis indicated that tumor size，AFP level were related to survival. Multivariate analysis demonstrated that tumor size，Child-Pugh score，hepatic cirrhosis and portal vein tumor thrombus were the independent prognostic factors(RR=3.07，4.43，7.05，14.02，P<0.01). ［Conclusion］ Small liver cancer has the same history of large liver cancer. Portal vein tumor thrombus is the most significant indicator for prognosis assessment. Early diagnosis and hepatic resection play an important role in improving survival. |
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