李月敏,李 杨,陈玉萍.胸腺神经内分泌肿瘤临床病理学亚型和诊治进展[J].肿瘤学杂志,2014,20(7):587-591. |
胸腺神经内分泌肿瘤临床病理学亚型和诊治进展 |
Progress in Clinicopathologic Subtypes of Neuroendocrine Tumor of the Thymus and Their Diagnosis and Treatment |
投稿时间:2013-10-24 |
DOI:10.11735/j.issn.1671-170X.2014.07.B013 |
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中文关键词: 胸腺肿瘤 神经内分泌肿瘤;类癌;预后 |
英文关键词:thymus neoplasms neuroendocrine tumor carcinoid carcinoma prognosis |
基金项目:中国博士后科学基金特别资助项目(201003778);北京市首都临床特色应用研究项目(Z121107001012060) |
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中文摘要: |
摘 要:胸腺神经内分泌肿瘤(neuroendocrine tumors of the thymus,NETT)是一种临床上罕见的位于前上纵隔的胸腺恶性肿瘤。它是一种主要或完全由神经内分泌细胞构成的上皮性肿瘤,需与含有散在的和成团的神经内分泌细胞的胸腺癌相鉴别。该病临床表现复杂多变且具有高度侵袭性。文章重点对NETT临床病理学亚型和诊治进展作一综述。 |
英文摘要: |
Abstract:Primary neuroendocrine tumor of the thymus (NETT) is a rare malignant tumor of the anterior mediastinum. NETT is an epithelial tumor predominantly or exclusively composed of neuroendocrine cells,which should differentiate with typical thymic carcinoma contained with scattered or clustered neuroendocrine tumors cells. NETTs are rare with only 250 cases have been described in the literature. Most are case report and small clinical series report. Clinical features of NETT are complex and the disease is highly aggressive. Progress in clinicopathologic subtypes of neuroendocrine tumor of the thymus and their diagnosis and treatment are reviewed. |
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