| 牟微娜,李 苗,谢长生.78例三阴性乳腺癌的临床特征和中医证型分析[J].肿瘤学杂志,2014,20(2):106-109. |
| 78例三阴性乳腺癌的临床特征和中医证型分析 |
| Clinical Features and TCM Syndromes in 78 Cases with Triple Negative Breast Cancer |
| 投稿时间：2013-08-18 |
| DOI：10.11735/j.issn.1671-170X.2014.02.B006 |
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| 中文关键词: 乳腺肿瘤 三阴性 临床特征 中医证型 |
| 英文关键词:breast neoplasms triple-negative phenotype clinical feature TCM syndromes |
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| 中文摘要: |
| 摘 要：［目的］ 分析并比较三阴性乳腺癌与非三阴性乳腺癌的临床病理特征、中医证型。［方法］ 收集经病理组织学证实并具有完整病例资料的乳腺癌患者437例，分为三阴性乳腺癌组和非三阴性乳腺癌组，收集两组患者的临床病理特征、舌象及脉象。［结果］ 三阴性乳腺癌组和非三阴性乳腺癌组在绝经状态、组织学分级、是否接受改良根治术、是否行术后辅助化疗以及中医证型分类上差异均有统计学意义（P<0.05）。［结论］ 与非三阴性乳腺癌相比，三阴性乳腺癌发病早，组织学分级更高，更多患者接受改良根治术，术后接受化疗者比例更高，两者中医证型存在不同，辨证治疗可改善三阴性乳腺癌患者临床症状，提高生存质量。 |
| 英文摘要: |
| Abstract：［Purpose］ To compare the clinical features and TCM syndromes in triple-negative (TNBC) and non-triple-negative (non-TNBC) breast cancer.［Methods］ A total of 437 cases with integrated clinical data were divided into two groups，TNBC group and non-TNBC group. Clinico- pathological features，display of tongue and pulse were analyzed.［Results］ Menopausal state，histological grade，surgical approach，with or without adjuvant chemotherapy and TCM syndromes were significantly different between TNBC group and non-TNBC group(P<0.05). ［Conclusion］ Compared with non-TNBC patients，TNBC patients have younger age，worse histological grade，and major patients with modified radical mastectomy and chemotherapy. TCM syndromes are different between the two groups. TCM differential treatment is able to improve clinical syndromes and the quality of life in patients with TNBC. |
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