| 杨 波,孙小扬,庞皓文.宫颈癌术后4种放疗方式的剂量学比较[J].肿瘤学杂志,2013,19(11):881-883. |
| 宫颈癌术后4种放疗方式的剂量学比较 |
| Dosimetric Analysis of Four Radiotherapy Techniques for Cervical Cancer Postoperation |
| 投稿时间：2013-06-29 |
| DOI：10.11735/j.issn.1671-170X.2013.11.B012 |
|
 |
| 中文关键词: 宫颈肿瘤 前后对穿照射 四野盒式照射 三维适形放疗 调强放疗 |
| 英文关键词:cervical neoplasms FBRT FFRT IMRT 3D-CRT |
| 基金项目: |
|
| 摘要点击次数: 2519 |
| 全文下载次数: 936 |
| 中文摘要: |
| 摘 要：［目的］ 分析宫颈癌术后前后对穿照射（FBRT）、四野盒式照射（FFRT）、三维适形(3D-CRT)和调强(IMRT)4种放疗技术的剂量学特点。［方法］ 收集8例宫颈癌术后放疗患者，分别设计FBRT、FFRT、3D-CRT和IMRT放疗计划；绘制出PTV的DVH示意图；比较各计划的靶区适形指数(CI )、均匀指数(HI)以及机器出束（MU）；计算小肠最大剂量Dmax、小肠和直肠受照40Gy以上体积（V40），并寻找左右股骨颈Dmax和V40最优的计划方式。［结果］ FBRT、FFRT、3D-CRT和IMRT的CI分别为0.32±0.09、0.35±0.08、0.61±0.09和0.83±0.14；HI分别为1.07±0.03、1.08±0.03、1.12±0.10和1.05±0.07；MU分别为5606±46、6451±49、6674±64、19321±141。PTV的DVH图以IMRT计划最优。小肠的Dmax和V40分别为5160±25、5139±24、5107±17、5078±23和76%±4%、57%±7%、34%±7%、29%±4%。直肠V40在IMRT中均值为45%，其余为100%；股骨颈Dmax在FFRT最大，为（5058±38）cGy；在IMRT最小，为（4762±31）cGy；股骨颈V40以3D-CRT最小，平均为7%±3%；FFRT最大，为19%±4%。［结论］ IMRT剂量分布最好，3D-CRT次之；在尚未具备条件开展IMRT的放疗单位开展3D-CRT也将使患者从中受益。 |
| 英文摘要: |
| Abstract：［Purpose］ To compare and analyze the dose distribution of front-back field radiotherapy（FBRT），four fields box of types in radiotherapy(FFRT)，three-dimensional conformal radiotherapy (3D-CRT) and intensity modulated radiotherapy (IMRT) for patients with cervical cancer postoperation. ［Methods］ Four radiotherapy plannings were designed for eight cases with cervical cancer postoperation. The conformal index (CI)，homogeneity index (HI) and delivered MU were computed；a diagram of DVH for PTV were drawn；the mean value of V40 for intestines，rectum and neck of femur，and the mean value of Dmax for intestines and neck of femur were calculated. ［Results］ The CI in FBRT，FFTR，3D-CRT and IMRT were 0.32±0.09，0.35±0.08，0.61±0.09 and 0.83±0.14；the HI were 1.07±0.03，1.08±0.03，1.12±0.10 and 1.05±0.07；MU were 5606±46，6451±49，6674±64，19321±141，respectively. The intestines Dmax was 5160±25，5139±24，5107±17，5078±23；and the intestines V40 was 76%±4%，57%±7%，34%±7%，29%±4%，respectively. The rectum V40 was 45% in IMRT，but it was 100% in the others. The Dmax of neck of femur met the maximum in FFRT(5058±38 cGy) and the minimum in IMRT(4762±31cGy). The V40 of neck of femur met the minimum in 3D-CRT (7%±3%) and the maximum in FFRT (19%±4%). ［Conclusion］ IMRT is the best choice for patients with cervical cancer postoperation，but if the patient in a radiotherapy unit which is not capable of performing IMRT，who also can benefit from the 3D-CRT. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |