| 黄素宁,潘林江,覃光灵.N0期鼻咽癌颈部可疑阳性淋巴结64Gy放疗疗效观察[J].肿瘤学杂志,2013,19(11):868-871. |
| N0期鼻咽癌颈部可疑阳性淋巴结64Gy放疗疗效观察 |
| The Efficacy of Cervical Suspicious Positive Lymph Nodes with 64Gy Radiotherapy in Patients with Nasopharyngeal Cancer Stage N0 |
| 投稿时间：2013-06-03 |
| DOI：10.11735/j.issn.1671-170X.2013.11.B009 |
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| 中文关键词: 鼻咽肿瘤 淋巴结 放射疗法 放射治疗剂量 |
| 英文关键词:nasopharyngeal neoplasms lymph nodes radiotherapy radiation dosage |
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| 中文摘要: |
| 摘 要：［目的］ 观察N0期鼻咽癌患者颈部可疑阳性淋巴结（最大横断面短径≥0.5cm但＜1cm、包膜完整、无中央坏死）给予放疗剂量64Gy时的疗效，患者的不良反应及预后。［方法］ 66例N0期鼻咽癌患者，颈部可疑阳性淋巴结予以64Gy的放疗剂量，以MRI检查为标准，评价疗效。［结果］放疗剂量达64Gy时颈部淋巴结转移灶完全缓解62例，有效率达93.9%，放疗前后淋巴结消退情况差异有统计学意义（P＜0.05）。在治疗结束时所有患者均出现Ⅰ级放射性皮炎，并在5年随访过程中无颈部淋巴结复发，无颈部皮下组织纤维化患者。［结论］ 64Gy的放疗剂量对鼻咽癌颈部可疑阳性淋巴结转移能很好地控制，且不良反应较轻，患者可耐受。 |
| 英文摘要: |
| Abstract:［Purpose］ To investigate the efficacy, toxicities and prognosis of cervical suspicious positive lymph nodes (maximum cross-sectional short diameter ≥0.5cm and <1cm, encapsulated, no central necrosis) with 64Gy radiotherapy in patients with nasopharyngeal cancer stage N0. ［Methods］ Sixty-six cases with nasopharyngeal cancer stage N0 with cervical suspicious positive lymph nodes were treated with 64Gy radiotherapy , and the efficacy was evaluated by MRI.［Results］ Complete response of cervical lymph node metastases with 64Gy radiotherapy was found in 62 cases，with response rate 93.9%. There was significant difference in lymph nodes subsiding before and after radiotherapy (P<0.05) .There was level Ⅰ radiodermatitis in all patients at the end of treatment. There was no cervical lymph node recurrence and neck fibrosis in 5-year follow-up.［Conclusion］ The 64Gy radiotherapy dose is suitable for the suspicious positive metastatic cervical lymph node, with less and tolerable toxicities. |
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