陈祖舜,赵荫农,吴飞翔.原发性透明细胞型肝癌手术切除后的预后影响因素分析[J].肿瘤学杂志,2013,19(10):797-800. |
原发性透明细胞型肝癌手术切除后的预后影响因素分析 |
Analysis of Prognostic Factors in Primary Clear Cell Carcinoma of the Liver Postoperation |
投稿时间:2013-07-10 |
DOI:10.11735/j.issn.1671-170X.2013.10.B012 |
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中文关键词: 肝肿瘤 透明细胞型 肝切除手术 预后 |
英文关键词:liver neoplasms clear cell carcinoma of the liver hepatectomy prognosis |
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中文摘要: |
摘 要:[目的] 探讨原发性透明细胞型肝癌(PCCCL)经手术切除治疗后影响预后的因素。[方法]回顾性分析广西医科大学附属肿瘤医院1996年1月至2006年12月间收治的52例PCCCL手术切除患者的临床资料,并进行单因素和多因素分析。[结果] 全组患者术后l、3、5年总生存率分别为80.8%、46.2%、38.5%。多因素分析提示患者预后与甲胎蛋白水平、是否发生血管浸润、肝硬化背景和有无包膜相关。[结论] 肿瘤包膜形成、大血管侵犯、甲胎蛋白水平、肝硬化背景是影响PCCCL患者预后的危险因素。 |
英文摘要: |
Abstract:[Purpose] To investigate the prognostic factors of primary clear cell carcinoma of the liver (PCCCL) postoperation.[Methods] The clinicopathological data of 52 patients with PCCCL treated with hepatectomy from January 1996 to December 2006 were retrospectively analyzed.[Results] The 1-,3- and 5-year overall survival(OS)rates for PCCCL patients were 80.8%,46.2% and 38.5%,respectively. Tumor capsule fomation,vascular invasion,liver cirrhosis and serum a-fetoprotein (AFP)level correlated with the survival of patients with PCCCL postoperation (P<0.05). [Conclusion] Tumor capsule formation,serum a-fetoprotein (AFP) level,large vascular invasion,liver cirrhosis are independent prognostic factors for prognosis of PCCCL. |
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