孟永斌,陈红云,翟笑枫.原发性肝癌患者肝动脉化疗栓塞术后疼痛的影响因素分析[J].肿瘤学杂志,2013,19(9):722-725.
原发性肝癌患者肝动脉化疗栓塞术后疼痛的影响因素分析
Influencing Factors on the Postoperative Pain of Transcatheter Arterial Chemoembolization in Patients with Primary Liver Cancer
投稿时间:2013-07-16  
DOI:10.11735/j.issn.1671-170X.2013.09.B013
中文关键词:  肝肿瘤  肝动脉化疗栓塞  疼痛  Logistic回归
英文关键词:liver neoplasms  transcatheter arterial chemoembolization(TACE)  pain  Logistic regression
基金项目:
作者单位
孟永斌 第二军医大学附属长海医院 
陈红云 第二军医大学附属长海医院 
翟笑枫 第二军医大学附属长海医院 
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中文摘要:
      摘 要: [目的] 探讨肝癌患者行经肝动脉化疗栓塞术(TACE)后疼痛的发生情况及影响因素。[方法] 对行TACE患者临床基线资料和术后疼痛发生情况进行分析,运用单因素和多因素Logistic回归方法统计分析与TACE术后疼痛发生相关的因素。[结果] 研究期间共115例有效病例,其中发生中重度疼痛46例,发生率40%,无疼痛及轻度疼痛69例,发生率60%。多因素Logistic回归提示,与TACE术后发生疼痛具有显著相关性的因素包括:术中使用明胶海绵(P<0.001)、肿瘤位置靠近肝包膜(2cm以内)(P=0.046)。[结论] 肝癌患者行TACE术后发生疼痛与术中使用明胶海绵、病灶位置靠近肝脏包膜有着显著关系。
英文摘要:
      Abstract:[Purpose] To investigate the occurrence of postoperative pain of transcatheter arterial chemoembolization (TACE) in patients with primary liver cancer and its related factors. [Methods] Clinical baseline data and postoperative pain of TACE were investigated,and the influencing factors on postoperative pain of TACE were analyzed by univariate and multivariate Logistic regression.[Results] During the study period a total of 115 cases were enrolled,with 46 cases of severe pain(40%);69 cases of no pain or mild pain(60%). Multivariate Logistic regression showed that influencing factors on postoperative pain of TACE included intraoperative use of gelatin sponge (P<0.001),tumor location near the liver capsule (2cm or less) (P=0.046).[Conclusion] Intraoperative use of gelatin sponge,and lesion located near the liver capsule are significantly correlated to postoperative pain of TACE in patients with primary liver cancer.
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