王 颖,刘植华.阴道乳酸杆菌与HPV感染、宫颈癌及癌前病变的相关性研究进展[J].肿瘤学杂志,2013,19(8):610-615.
阴道乳酸杆菌与HPV感染、宫颈癌及癌前病变的相关性研究进展
Research Progress in Correlation of Vaginal Lactobacillus with HPV Infection,Cervical Cancer and Precancerous Lesions
投稿时间:2013-05-02  
DOI:10.11735/j.issn.1671-170X.2013.08.B006
中文关键词:  乳酸杆菌  人乳头状瘤病毒  宫颈肿瘤  癌前病变
英文关键词:lactobacillus  human papilloma virus(HPV)  cervical neoplasms  precancerous lesion
基金项目:
作者单位
王 颖 广州医科大学研究生院 
刘植华 深圳市妇幼保健院 
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中文摘要:
      摘 要:乳酸杆菌及其代谢产物具有抑制肿瘤的作用,通过产生各种代谢产物干扰肿瘤代谢,以及激活机体免疫功能而发挥作用。乳酸杆菌在防治各种肿瘤中的作用也已引起重视。阴道乳酸杆菌是构成阴道微环境的重要因素,其数量的减少与HPV感染、宫颈癌前病变及宫颈癌有关。文章就阴道乳酸杆菌与HPV感染、宫颈癌及癌前病变的关系进行综述。
英文摘要:
      Abstract: Previous studies had demonstrated that lactobacillus had antitumor effect. It interfe-rences tumor metabolism through the production of metabolites and activates the immune function. Effect of lactobacillus in the prevention and treatment for various tumors has aroused attention. Lactobacillus is a dominated factor in normal women’s vaginal environment. Decreasing of vaginal lactobacillus related to human papilloma virus(HPV) infection,cervical cancer and precancerous lesions. The relationship of lactobacillus with HPV infection,cervical cancer and cervical precancerous lesions is reviewed.
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