| 邵 岚.宫颈冷刀锥切术诊治宫颈上皮内瘤变的价值[J].肿瘤学杂志,2012,18(6):460-462. |
| 宫颈冷刀锥切术诊治宫颈上皮内瘤变的价值 |
| Value of Cervical Cold Knife Conization in the Diagnosis and Treatment for Cervical Intraepithelial Neoplasia |
| 投稿时间：2012-04-26 |
| DOI： |
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| 中文关键词: 宫颈上皮内瘤病 宫颈锥切术 活检 病理学 |
| 英文关键词:cervical intraepithelial neoplasia cervical conization biopsy pathology |
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| 中文摘要: |
| 摘 要:［目的］ 探讨宫颈冷刀锥切术对宫颈上皮内瘤变（CIN）的诊断及治疗作用。［方法］ 对比126例行宫颈冷刀锥切术和阴道镜下多点活检的CIN患者的病理检查结果，分析CIN患者行宫颈冷刀锥切术的临床疗效和并发症。［结果］ 阴道镜下多点活检和宫颈冷刀锥切术后病理完全符合83例（占65.9%）。14例(11.1% )患者锥切边缘受累;发现早期浸润癌5例，其中2例早期浸润癌仅行宫颈锥切，随访无复发。宫颈冷刀锥切术的主要并发症为出血和宫颈管狭窄，发生率分别为6.3% (8／126)和3.9% (5／126)。［结论］ 宫颈锥切术比阴道镜下多点活检对宫颈上皮内瘤变的诊断更准确，并具有重要治疗作用。 |
| 英文摘要: |
| Abstract:［Purpose］ To investigate the diagnostic and therapeutic efficacy of cold knife conization for cervical intraepithelial neoplasia(CIN).［Methods］ Pathologic findings of cervical cold knife conization and colposcopic multiple punch biopsies were compared in 126 cases with CIN， and the clinical efficacy and complications of cold knife conization were analyzed.［Results］ Pathologic findings of colposcopic multiple punch biopsies and cervical cold knife conization were full compliance in 83 cases(65.9%). Conization margin involved in 14 cases,and early invasive cancer in 5 cases were found. Two cases with early invasive cancer were treated with conization alone without recurrence in the follw-up period.The main complications associated with conization were haemorrhage(6.3%，8／126) and cervical stenosis(3.9%，5／126)．［ Conclusion］ CIN diagnosis with conization is more accurate than that with colposcopic multiple punch biopsies．And it plays an important role in the treatment for CIN and early invasive cancer． |
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