| 廖希一,林少俊,吴君心.锥形束CT研究头颈部肿瘤调强放疗摆位误差[J].肿瘤学杂志,2013,19(4):249-252. |
| 锥形束CT研究头颈部肿瘤调强放疗摆位误差 |
| A Clinical Evaluation of Setup Errors in IMRT Using Cone Beam CT for Head and Neck Cancer |
| 投稿时间：2012-04-25 |
| DOI：10.11735/j.issn.1671-170X.2013.04.B2012200 |
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| 中文关键词: 锥形束CT 调强放疗 摆位误差 头颈部肿瘤 |
| 英文关键词:cone beam CT intensity modulation radiation therapy setup error head and neck neoplasms |
| 基金项目:福建省临床重点专科建设项目（2012年） |
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| 中文摘要: |
| 摘 要:［目的］ 应用IGRT机载千伏级锥形束CT(CBCT)研究头颈部肿瘤调强放疗体位的线性误差和旋转误差。［方法］ 应用医科达Synergy IGRT系统治疗头颈部肿瘤12例，共治疗217次。CBCT分别在治疗前、治疗中（摆位误差纠正后）、治疗后共扫描3次，得到3组X线容积图像（XVI），将3组XVI图像和计划CT图像的靶中心匹配，获得3组X、Y、Z三维方向的线性误差和旋转误差。［结果］ 12例每次治疗开始前的CBCT共217次，线性误差在X、Y、Z方向上系统误差(均数)±随机误差(标准差)分别为 (-0.04±2.63)mm、(0.07±1.69)mm、(-1.15±1.33)mm，旋转误差为(0.10°±1.14°)、(0.16°±1.41°)、(-0.06°±1.22°)。纠正后的X、Y、Z 3个方向线性误差及旋转误差的系统误差和随机误差均低于纠正前水平。治疗中（摆位误差纠正后）与治疗后的误差结果无显著性差异。［结论］ CBCT实时纠正头颈部肿瘤放疗的摆位误差可缩小摆位误差并减少计划肿瘤靶区（PTV）外扩。头颈部肿瘤患者分次治疗中的摆位误差小。 |
| 英文摘要: |
| Abstract:［Purpose］To investigate the linear and rotational setup errors in intensity modulated radiation therapy (IMRT) using kV cone beam CT (CBCT) on IGRT for head and neck cancer. ［Methods］ Twelve patients with head and neck carcinoma were treated by Elekta Synergy IGRT with a total of 217 times．X-ray volumetric images(XVI) acquired pre-，intra-（after correcting the setup error），and post-radiation，were compared with planned CT images to get informations of linear and rotational setup errors of X-axis，Y-axis，Z-axis.［Results］ A total of 217 CBCT scans were applied for 12 patients pre-radiation．The systemic±random errors on linear X，Y，Z directions were (-0.04±2.63)mm，(0.07±1.69)mm，(-1.15±1.33)mm，on rotational X，Y，Z directions were (0.10°±1.14°)、(0.16°±1.41°)、(-0.06°±1.22°)respectively． After correction of all the setup errors，both the systematic errors and random errors were obviously less than those before correction．The difference of setup errors between intra-radiation（after correcting the setup error）and post-radiation was not significant．［Conclusion］ Real-time correction of setup error in patients with head and neck cancer by CBCT can reduce the setup error and decrease planning target volume(PTV) extending． And the setup error in fractionated radiation for head and neck cancer is small． |
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