徐 栋,徐加英,王晓莹.血清CA125结合超声造影检查对子宫肌瘤与子宫腺肌症的鉴别诊断价值[J].肿瘤学杂志,2012,18(12):956-959.
血清CA125结合超声造影检查对子宫肌瘤与子宫腺肌症的鉴别诊断价值
Clinical Value of Serum CA125 Combined with Contrast Enhanced Ultrasound in Differential Diagnosis for Hysteromyoma and Adenomyosis
投稿时间:2012-09-14  
DOI:
中文关键词:  子宫肌瘤  子宫腺肌症  血清  CA125  超声检查  造影剂
英文关键词:hysteromyoma  adenomyosis  serum  CA125  ultrasonography  contrast media
基金项目:杭州萧山科技计划项目(2011321)
作者单位
徐 栋 浙江萧山医院 
徐加英 浙江萧山医院 
王晓莹 浙江萧山医院 
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中文摘要:
      摘 要:[目的] 探讨血清CA125结合超声造影检查对子宫肌瘤与子宫腺肌症的鉴别诊断价值。 [方法] 对73例临床诊断为子宫局灶性病变的患者进行血清CA125检测、常规腔内超声及超声造影检查,并与术后组织病理结果比较。[结果] 73例患者中27例(37.0%)为子宫腺肌症,46例(63.0%)为子宫肌瘤;CA125阳性24例(32.9%)。血清CA125阳性患者中,79.2%(19/24)经术后病理确诊为子宫腺肌症;血清CA125阴性患者中,83.7%(41/49)经术后病理确诊为子宫肌瘤,两者差异有统计学意义(P<0.01)。27例子宫腺肌症超声造影表现为绝大多数病灶内部呈不均匀增强,占74.1%(20/27);46例子宫肌瘤超声造影表现为绝大多数病灶区环状不均匀强化,占87.0%(40/46),两者差异有统计学意义(P<0.01)。[结论] 血清CA125结合超声造影检查,可为子宫肌瘤与子宫腺肌症的鉴别诊断提供更准确的信息,具有重要的临床应用价值。
英文摘要:
      Abstract: [Purpose] To explore the clinical value of serum CA125 combined with contrast enhanced ultrasound in differential diagnosis for hysteromyoma and adenomyosis. [Methods] Serum CA125 detection,endocavity ultrasound examination and contrast enhanced ultrasound were performed in 73 patients with focal uterine lesions.All cases were confirmed by postoperative histopathologic findings.[Results] Of 73 patients,27 cases(37.0%) were adenomyosis; 46 cases (63.0%) were hysteromyoma. Serum CA125 was positive in 24 cases (32.9%). Of 24 cases with serum CA125 positive,79.2%(19/24) were confirmed adenomyosis by postoperative pathology;Of 49 cases with serum CA125 negative,83.7%(41/49) were confirmed hysteromyoma by postoperative pathology. There was significant difference between them (P<0.01). Of 27 cases with adenomyosis,74.1%(20/27) showed irregular and unhomogeneous enhancement in the whole lesion; and of 46 cases with hysteromyoma,87.0%(40/46) showed annularity irregular enhancement. There was significant difference between them(P<0.01). [Conclusion] Serum CA125 combined with contrast enhanced ultrasound provides more accurate information in the differential diagnosis for hysteromyoma and adenomyosis.It is of great value in clinical application.
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