| 徐 栋,徐加英,王晓莹.血清CA125结合超声造影检查对子宫肌瘤与子宫腺肌症的鉴别诊断价值[J].肿瘤学杂志,2012,18(12):956-959. |
| 血清CA125结合超声造影检查对子宫肌瘤与子宫腺肌症的鉴别诊断价值 |
| Clinical Value of Serum CA125 Combined with Contrast Enhanced Ultrasound in Differential Diagnosis for Hysteromyoma and Adenomyosis |
| 投稿时间：2012-09-14 |
| DOI： |
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| 中文关键词: 子宫肌瘤 子宫腺肌症 血清 CA125 超声检查 造影剂 |
| 英文关键词:hysteromyoma adenomyosis serum CA125 ultrasonography contrast media |
| 基金项目:杭州萧山科技计划项目（2011321） |
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| 中文摘要: |
| 摘 要：［目的］ 探讨血清CA125结合超声造影检查对子宫肌瘤与子宫腺肌症的鉴别诊断价值。 ［方法］ 对73例临床诊断为子宫局灶性病变的患者进行血清CA125检测、常规腔内超声及超声造影检查，并与术后组织病理结果比较。［结果］ 73例患者中27例（37.0%）为子宫腺肌症，46例（63.0%）为子宫肌瘤；CA125阳性24例（32.9%）。血清CA125阳性患者中，79.2%（19/24）经术后病理确诊为子宫腺肌症；血清CA125阴性患者中，83.7%（41/49）经术后病理确诊为子宫肌瘤，两者差异有统计学意义（P<0.01）。27例子宫腺肌症超声造影表现为绝大多数病灶内部呈不均匀增强，占74.1%（20/27）；46例子宫肌瘤超声造影表现为绝大多数病灶区环状不均匀强化，占87.0%（40/46），两者差异有统计学意义（P<0.01）。［结论］ 血清CA125结合超声造影检查，可为子宫肌瘤与子宫腺肌症的鉴别诊断提供更准确的信息，具有重要的临床应用价值。 |
| 英文摘要: |
| Abstract: ［Purpose］ To explore the clinical value of serum CA125 combined with contrast enhanced ultrasound in differential diagnosis for hysteromyoma and adenomyosis. ［Methods］ Serum CA125 detection，endocavity ultrasound examination and contrast enhanced ultrasound were performed in 73 patients with focal uterine lesions.All cases were confirmed by postoperative histopathologic findings.［Results］ Of 73 patients，27 cases(37.0%) were adenomyosis； 46 cases (63.0%) were hysteromyoma. Serum CA125 was positive in 24 cases (32.9%). Of 24 cases with serum CA125 positive，79.2%（19/24） were confirmed adenomyosis by postoperative pathology；Of 49 cases with serum CA125 negative，83.7%（41/49） were confirmed hysteromyoma by postoperative pathology. There was significant difference between them (P<0.01). Of 27 cases with adenomyosis，74.1%（20/27） showed irregular and unhomogeneous enhancement in the whole lesion； and of 46 cases with hysteromyoma，87.0%（40/46） showed annularity irregular enhancement. There was significant difference between them(P<0.01). ［Conclusion］ Serum CA125 combined with contrast enhanced ultrasound provides more accurate information in the differential diagnosis for hysteromyoma and adenomyosis.It is of great value in clinical application. |
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