刘洵祺,熊海林,李 俊.进展期胃癌术后早期复发的临床病理因素分析[J].肿瘤学杂志,2012,18(10):757-761.
进展期胃癌术后早期复发的临床病理因素分析
Analysis of Clinicopathological Factors of Early Recurrence in Patients with Advanced Gastric Carcinoma Postoperation
投稿时间:2012-05-07  
DOI:
中文关键词:  胃肿瘤  外科手术  复发  危险因素
英文关键词:stomach neoplasms  surgical procedures  recurrence  risk factors
基金项目:广东省自然科学基金项目资助(1051600101000001)
作者单位
刘洵祺 中山大学 
熊海林 中山大学附属惠州医院 
李 俊 中山大学附属惠州医院 
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中文摘要:
      摘 要:[目的] 探讨进展期胃癌术后复发的时间和影响因素。[方法] 回顾性分析155例进展期胃癌术后复发患者的临床病理资料,采用χ2检验进行单因素分析,Logistic回归进行多因素分析进展期胃癌患者术后复发的相关因素。[结果] 155例患者平均复发时间为术后12.6个月。其中早期复发(距首次手术≤1年)94例(60. 6%),晚期复发(距首次手术>1年)61例(39.4%)。单因素分析显示,胃癌术后早期复发与肿瘤直径、Borrmann分型、分化程度、浸润深度、淋巴结转移、TNM分期有关(P<0. 05)。多因素Logistic结果显示,TNM分期和淋巴结转移是进展期胃癌术后早期复发的独立危险因素(P<0.05) 。[结论] TNM分期和淋巴结转移是预测进展期胃癌术后早期复发的重要因素。
英文摘要:
      Abstract: [Purpose] To investigate the time and influencing factors of recurrence in patients with advanced gastric cancer postoperation.[Methods] Clinicopathological data of 155 patients with advanced gastric cancer postoperative recurrence were analyzed retrospectively with χ2 test and multivariate Logistic regression analysis.[Results] The mean time of recurrence was 12.6 months from primary surgery. Patients were divided into early recurrence group(recurrence within one year after surgery) 94 cases(60.6%);and late recurrence group(recurrence ≥1 year after surgery) 61 cases(39.4%). Univariate analysis showed that the tumor diameter,Borrmann type,differentiation,depth of invasion,lymph node metastases and TNM staging correlated to the time of recurrence(P<0.05). Multivariate Logistic regression analysis showed that TNM staging and lymph node metastases were independent factors related to early recurrence(P<0.05).[Conclusion] TNM stage and lymph node metastases are important factors to predict early recurrence in patients with advanced gastric cancer postoperation.
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