| 叶 慧,李 杨,莫 逸.18F-FDG PET/CT显像在胰腺癌诊断中的应用价值[J].肿瘤学杂志,2012,18(10):734-737. |
| 18F-FDG PET/CT显像在胰腺癌诊断中的应用价值 |
| The Applications of 18F-FDG PET/CT in the Diagnosis for Pancreatic Cancer |
| 投稿时间：2012-09-03 |
| DOI： |
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| 中文关键词: PET/CT 胰腺肿瘤 体层摄影术，X线计算机 |
| 英文关键词:PET/CT pancreatic neoplasms tomography,X-ray computed |
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| 摘要点击次数: 1673 |
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| 中文摘要: |
| 摘 要：［目的］ 评价18F-脱氧葡萄糖（18F-FDG）PET/CT显像在胰腺癌诊断中的应用价值。［方法］ 回顾性分析46例疑似胰腺癌患者的全身18F-FDG PET/CT及CT平扫加增强的影像学资料，比较两者对胰腺癌的诊断价值。［结果］ 46例疑似胰腺癌患者中，44例经手术、腹腔镜取病理确诊，其中胰腺癌38例，慢性胰腺炎6例，另2例PET/CT发现多处肝转移或肺转移，因而放弃手术，经临床随访1年后确诊为胰腺癌。18F-FDG PET/CT检查阳性37例，灵敏度92.5％，特异性83.3%，准确率为91.3%；CT平扫加增强检查，灵敏度75.0％，特异性66.7%，准确率为73.9%。PET/CT对胰腺癌诊断的灵敏度、特异性、准确率均明显高于CT，两者差异有统计学意义（P<0.05）。［结论］ 18F-FDG PET/CT对胰腺癌的诊断与分期有较高的临床应用价值。 |
| 英文摘要: |
| Abstract: ［Purpose］ To evaluate the value of F-18 fluorodeoxyglucose(FDG)-positron emission tomography(PET) in the diagnosis for pancreatic cancer. ［Methods］ Imaging data of 18F-FDG PET/CT and CT plain scan plus contrast scan for 46 cases suspected with pancreatic cancer were analyzed retrospectively，and the diagnostic value of them were compared. ［Results］ Of 46 cases suspected with pancreatic cancer，44 cases were confirmed by surgery or laparoscopy，with 38 cases pancreatic cancer and 6 cases chronic pancreatitis. Another 2 cases gave up surgery because of liver metastasis or lung metastasis diagnosed by 18F-FDG PET/CT and were confirmed with pancreatic cancer in 1 year’s follow-up. 18F-FDG PET/CT showed positive in 37 cases，with sensitivity of 92.5％，specificity of 83.3%，and accuracy of 91.3% in detecting pancreatic cancer in 46 patients，while those for CT were 75.0％，66.7%，and 73.9%，respectively. The sensitivity，specificity and accuracy of 18F-FDG PET/CT were higher than those of CT，with significant difference between them(P<0.05). ［Conclusion］ 18F-FDG PET/CT might have an important value in the diagnosis and staging for pancreatic cancer. |
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