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| 2018-2022年湖南省长沙市甲状腺癌流行特征及趋势分析 |
| Epidemiologic Characteristics and Trends of Thyroid Cancer in Changsha, Hunan Province from 2018 to 2022 |
| 投稿时间：2026-02-26 修订日期：2026-05-09 |
| DOI： |
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| 中文关键词: 甲状腺癌 发病率 死亡率 趋势 长沙 湖南 |
| 英文关键词:thyroid cancer incidence mortality Changsha Hunan |
| 基金项目: |
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| 摘要点击次数: 44 |
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| 中文摘要: |
| [目的] 分析2018-2022年长沙市甲状腺癌流行特征及变化趋势。[方法] 收集并整理长沙市肿瘤登记地区上报的甲状腺癌发病与死亡数据，计算不同性别、不同地区甲状腺癌的的粗发病（死亡）率、中国人口标准化发病（死亡）率、世界人口标准化发病（死亡）率、年龄别发病（死亡）率，0~74岁累积发病（死亡）率。采用Joinpoint4.9软件计算年度变化百分比（annual percentage change，APC）来分析甲状腺癌的发病、死亡变化趋势。[结果] 2018-2022年长沙市甲状腺癌粗发病率为25.14/10万，中标发病率为23.40/10万，世标发病率为19.44/10万，0-74岁累积发病率为1.72%，女性中标发病率是男性的2.65倍，城市中标发病率是农村的1.46倍；粗死亡率为0.92/10万，中标死亡率为0.56/10万，世标死亡率为0.61/10万，0-74岁累积死亡率为0.06%，女性中标死亡率是男性的1.73倍，城市中标死亡率是农村的1.76倍。甲状腺癌年龄别发病率在30-34岁组达到高峰，死亡率在≥85岁组达到高峰。2018-2022年长沙市全人群甲状腺癌粗发病率(APC=34.4%, t=7.5, P=0.005)、中标发病率(APC=37.6%, t=7.6, P=0.005)均呈上升趋势，男性粗发病率(APC=30.6%, t=9.2, P=0.003)、中标发病率(APC=34.5%, t=8.6, P=0.003)均呈上升趋势，女性粗发病率(APC=35.6%, t=7, P=0.006)、中标发病率(APC=38.5%, t=7.3, P=0.005)均呈显著上升趋势；全人群甲状腺癌粗死亡率(APC=15.7%, t=16.7, P<0.001)、中标死亡率(APC=15.6%, t=16.3, P=0.001)均呈上升趋势，农村甲状腺癌粗死亡率(APC=37.6%, t=4.3, P=0.023)、中标死亡率(APC=44.3%, t=6.4, P=0.008)均呈显著上升趋势，城市地区死亡率变化趋势平稳，差异无统计学意义（P>0.05）。[结论] 2018-2022年长沙市甲状腺癌发病率和死亡率均呈上升趋势，特别是女性群体和农村地区，应作为长沙市甲状腺癌防控的重点。 |
| 英文摘要: |
| [Objective] To analyze the epidemiological characteristics and trends of thyroid cancer in Changsha from 2018 to 2022. [Methods] The incidence and mortality data of thyroid cancer were collected and organized from Changsha cancer registration areas. The crude incidence/mortality rates, age-standardized incidence/mortality rates by Chinese standard population (ASIRC, ASMRC), age-standardized incidence/mortality rates by world standard population (ASIRW, ASMRW), age-specific incidence/mortality rates, and the cumulative incidence/mortality rates(0–74 years old) were calculated by gender and areas. Joinpoint 4.9 software was used to calculate the annual percentage change (APC) for analyzing the trends of the incidence and mortality. [Results] The crude incidence rate of thyroid cancer in Changsha from 2018 to 2022 was 25.14/105, with the ASIRC of 23.40/105 , ASIRW of 19.44/105, and the cumulative incidence rates(0–74 years old) of 1.72%. The ASIRC in females was 2.65 times that in males, and the ASIRC in urban areas was 1.46 times that in rural areas. The crude mortality rate was 0.92/105, with the ASMRC of 0.56/105, ASMRW of 0.61/105, and the cumulative mortality rates(0–74 years old) of 0.06%. The ASMRC in females was 1.73 times that in males, and the ASMRC in urban areas was 1.76 times that in rural areas. The age-specific incidence rate of thyroid cancer peaked in the 30–34 age group, and the mortality rate peaked in the ≥85 age group. From 2018 to 2022, the crude incidence rate and ASIRC of thyroid cancer showed an upward trend in whole population (APC=34.4%, t=7.5, P=0.005; APC=37.6%, t=7.6, P=0.005), in male (APC=30.6%, t=9.2, P=0.003; APC=34.5%, t=8.6, P=0.003) and female (APC=35.6%, t=7, P=0.006; APC=38.5%, t=7.3, P=0.005). The crude mortality rate and ASMRC of thyroid cancer showed an upward trend in whole population(APC=15.7%, t=16.7, P<0.001; APC = 15.6%, t=16.3, P=0.001), in rural areas (APC=37.6%, t=4.3, P=0.023; APC=44.3%, t=6.4, P=0.008), while the mortality trend in urban areas was stable with no statistical significance(P>0.05). [Conclusions] The incidence and mortality of thyroid cancer in Changsha showed an upward trend from 2018 to 2022, especially among females and rural areas, which should be the focus of thyroid cancer prevention and control in Changsha. |
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